NEURON-SPECIFIC ENOLASE REDUCTION IN IRRADIATED SALIVARY-GLANDS OF THE RAT - AN IMMUNOHISTOCHEMICAL STUDY

被引：5
作者：
SAITOH, K
TOYOOKA, M
FUJITA, K
HASHIMOTO, J
KUNIKATA, M
MORI, M
机构：
[1] ASAHI UNIV,SCH DENT,DEPT ORAL & MAXILLOFACIAL SURG,HOZUMI,GIFU 50102,JAPAN
[2] MEIKAI UNIV,SCH DENT,DEPT ORAL SURG,SAKADO,SAITAMA,JAPAN
来源：
ACTA HISTOCHEMICA | 1992年 / 93卷 / 01期
关键词：
D O I：
10.1016/S0065-1281(11)80223-0
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Neuron-specific enolase (NSE) in the salivary glands of normal and irradiated rats was studied by immunohistochemical methods. The normal salivary gland of Sprague-Dawley rats (465 g) showed positive staining for NSE in striated ducts and granular convoluted tubule (GCT) cells. A single radiation, TDF (time, dose, fractionation factor) 100 and 200 (18.82 Gy and 27.97 Gy, respectively) was done, and 4 groups (1, 2, 3 and 4 weeks after radiation) of 5 rats each were used. Irradiated salivary glands indicated a remarkable reduction of NSE staining in GCT cells and a reduction but to a lesser degree in the striated duct of the submandibular gland. Immunohistochemical deposition of NSE was not changed in die sublingual glands of irradiated rats. The reduction of NSE immunodeposition was irradiation dose dependent.
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收藏
页码：277 / 281
页数：5
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