LIQUID-CHROMATOGRAPHIC DETERMINATION OF VITAMIN-K-1 IN INFANT FORMULAS AND MILK

被引：0

作者：

INDYK, HE ^{[1
]}

LITTLEJOHN, VC ^{[1
]}

LAWRENCE, RJ ^{[1
]}

WOOLLARD, DC ^{[1
]}

机构：

[1] MINIST AGR & FISHERIES,LUNFIELD FOOD SERV CTR,AUCKLAND,NEW ZEALAND

来源：

JOURNAL OF AOAC INTERNATIONAL | 1995年 / 78卷 / 03期

关键词：

D O I：

暂无

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Vitamin K-1 in infant formulas and milk products is determined by reversed-phase liquid chromatography (LC) with UV detection. The sample is hydrolyzed enzymatically, and the vitamin is extracted with hexane. Fractionation by normal-phase semipreparative LC is followed by analytical LC, with quantitation by the internal standard technique. Recovery of the analyte was 97.4 +/- 2.8%. Linearity was established between 0.05 and 4.0 mu g/mL. The limit of quantitation is 0.5 mu g/100 g for milk powder, which allows the method to quantitate endogenous levels of vitamin K-1.

引用

页码：719 / 723

页数：5

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