Pegylated Interferon and Ribavirin Treatment of Chronic Hepatitis C Coinfection in a Patient with Human Immunodeficiency Virus Infection

被引:0
作者
Kaptan, Figen [1 ]
Turker, Nesrin [1 ]
Ormen, Bahar [1 ]
El, Sibel [1 ]
Hekimoglu, Can Huseyin [1 ]
Vardar, Ilknur [1 ]
Ural, Serap [1 ]
Sener, Asli Gamze [2 ]
Coskun, Nejat Ali [1 ]
机构
[1] Izmir Ataturk Egitim & Arastirma Hastanesi, Infeksiyon Hastaliklari & Klin Mikrobiyol Klin, Izmir, Turkey
[2] Izmir Ataturk Egitim & Arastirma Hastanesi, Tibbi Mikrobiyol Lab, Izmir, Turkey
关键词
HIV; HCV antibodies; coinfection; pegylated interferon alpha 2a; ribavirin;
D O I
10.5152/kd.2011.30
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Human immunodeficiency virus (HIV) and hepatitis C virus (HCV)coinfection is seen frequently due to similar routes of transmission. In coinfected patients, progression of chronic hepatitis C (CHC) infection is accelerated. In this study, a 44-year old male patient with HIV/HCV (genotype 1b) coinfection is evaluated. For the treatment of CHC, pegylated interferon alpha 2a 180 mg per week and ribavirin 1000 mg/day were used for 48 weeks and sustained virologic response was achieved. During the course of CHC treatment no adverse effect was seen.
引用
收藏
页码:122 / 125
页数:4
相关论文
共 38 条
[1]   Short statement of the first European consensus conference on the treatment of chronic hepatitis B and C in HIV co-infected patients [J].
Alberti, A ;
Clumeck, N ;
Collins, S ;
Gerlich, W ;
Lundgren, J ;
Palù, G ;
Reiss, P ;
Thiebaut, R ;
Weiland, O ;
Yazdanpanah, Y ;
Zeuzem, S .
JOURNAL OF HEPATOLOGY, 2005, 42 (05) :615-624
[2]   Epidemiology of viral hepatitis and HIV co-infection [J].
Alter, MJ .
JOURNAL OF HEPATOLOGY, 2006, 44 :S6-S9
[3]   Risk factors for symptomatic mitochondrial toxicity in HIV/hepatitis C virus-coinfected patients during interferon plus ribavirin-based therapy [J].
Bani-Sadr, F ;
Carrat, F ;
Pol, S ;
Hor, R ;
Rosenthal, E ;
Goujard, C ;
Morand, P ;
Lunel-Fabiani, F ;
Salmon-Ceron, D ;
Piroth, L ;
Pialoux, G ;
Bentata, M ;
Cacoub, P ;
Perronne, C .
JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 2005, 40 (01) :47-52
[4]   Early virologic failure in HIV-coinfected hepatitis C patients treated with the peginterferon-ribavirin combination - Does abacavir play a role? [J].
Bani-Sadr, Firouze ;
Denoeud, Lise ;
Morand, Patrice ;
Lunel-Fabiani, Francoise ;
Pol, Stanislas ;
Cacoub, Patrice ;
Perronne, Christian ;
Carrat, Fabrice .
JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 2007, 45 (01) :123-125
[5]   Liver fibrosis progression in human immunodeficiency virus and hepatitis C virus coinfected patients [J].
Benhamou, Y ;
Bochet, M ;
Di Martino, V ;
Charlotte, F ;
Azria, F ;
Coutellier, A ;
Vidaud, M ;
Bricaire, F ;
Opolon, P ;
Katlama, C ;
Poynard, T .
HEPATOLOGY, 1999, 30 (04) :1054-1058
[6]   Increasing mortality due to end-stage liver disease in patients with human immunodeficiency virus infection [J].
Bica, I ;
McGovern, B ;
Dhar, R ;
Stone, D ;
McGowan, K ;
Scheib, R ;
Snydman, DR .
CLINICAL INFECTIOUS DISEASES, 2001, 32 (03) :492-497
[7]  
Butt AA, 2009, HIV CLIN TRIALS, V10, P25, DOI [10.1310/hct1001-025, 10.1310/hct1001-25]
[8]   Peginterferon alfa-2a plus ribavirin versus interferon alfa-2a plus ribavirin for chronic hepatitis C in HIV-coinfected persons [J].
Chung, RT ;
Andersen, J ;
Volberding, P ;
Robbins, GK ;
Liu, T ;
Sherman, KE ;
Peters, MG ;
Koziel, MJ ;
Bhan, AK ;
Alston, B ;
Colquhoun, D ;
Nevin, T ;
Harb, G ;
van der Horst, C .
NEW ENGLAND JOURNAL OF MEDICINE, 2004, 351 (05) :451-459
[9]  
de Ledinghen V, 2006, JAIDS-J ACQ IMM DEF, V41, P175
[10]  
Erbay A, 2003, TURK HIV AIDS DERG, V6, P43