NEW EFFICIENT PROTOCOL FOR ARYNE GENERATION - SELECTIVE SYNTHESIS OF DIFFERENTIALLY PROTECTED 1,4,5-NAPHTHALENETRIOLS

被引：138

作者：

MATSUMOTO, T ^{[1
]}

HOSOYA, T ^{[1
]}

KATSUKI, M ^{[1
]}

SUZUKI, K ^{[1
]}

机构：

[1] KEIO UNIV,DEPT CHEM,KOHOKU KU,YOKOHAMA,KANAGAWA 223,JAPAN

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 46期

关键词：

D O I：

10.1016/S0040-4039(00)93589-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Arynes are generated cleanly and rapidly by halogen-lithium exchange of ortho-haloaryl triflates with n-BuLi at -78-degrees-C. [2+4]-Cycloaddition of alpha-alkoxyaryne with 2-methoxyfuran proceeded regioselectively (head-to-head) to afford 1,4,5-naphthalenetriols.

引用

页码：6735 / 6736

页数：2

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