PREVENTIVE TREATMENT OF MIGRAINE HEADACHE WITH A NEW ISOERGOLENYL DERIVATIVE

被引：5

作者：

HERRMANN, WM ^{[1
]}

KRISTOF, M ^{[1
]}

SASTREYHERNANDEZ, M ^{[1
]}

机构：

[1] SCHERING AG, DEPT CLIN NEUROPSYCHOPHARMACOL, BERLIN, GERMANY

来源：

JOURNAL OF INTERNATIONAL MEDICAL RESEARCH | 1978年 / 6卷 / 06期

关键词：

D O I：

10.1177/030006057800600611

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

In the present double-blind clinical trial an isoergolenyl derivative with periphal antiserotonin, central dopaminergic activity and a-increasing effect on the human EEG, lisuride hydrogen maleate, was tested against placebo in a six-month trial involving 240 patients. Lisuride in long-term administration significantly reduces the frequency of migraine attacks in comparison to placebo. Its advantages are good tolerance and minimal side-effects. It is therefore concluded that lisuride is a suitable and effective drug for the prevention of migraine. © 1978, SAGE Publications. All rights reserved.

引用

页码：476 / 482

页数：7

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