Imaging of Tumor Angiogenesis for Radiologists-Part 1: Biological and Technical Basis

被引：42

作者：

Garcia-Figueiras, Roberto ^{[1
]}

Padhani, Anwar R. ^{[2
]}

Beer, Ambros J. ^{[3
]}

Baleato-Gonzalez, Sandra ^{[1
]}

Vilanova, Joan C. ^{[4
]}

Luna, Antonio ^{[5
,6
]}

Oleaga, Laura ^{[7
]}

Gomez-Caamano, Antonio ^{[8
]}

Koh, Dow-Mu ^{[9
]}

机构：

[1] Hosp Clin Univ Santiago de Compostela, Dept Radiol, Choupana S-N, Santiago De Compostela 15706, Spain

[2] Mt Vernon Canc Ctr, Paul Strickland Scanner Ctr, Northwood, Middx, England

[3] Univ Klinikum Ulm, Klin Nukl Med, Ulm, Germany

[4] Univ Girona, Dept Radiol, Clin Girona, IDI, Girona, Spain

[5] Hlth Time, Clin Nieves SERCOSA, Jaen, Spain

[6] Case Western Reserve Univ, Dept Radiol, Cleveland, OH 44106 USA

[7] Hosp Clin Barcelona, Dept Radiol, Barcelona, Spain

[8] Hosp Clin Univ Santiago de Compostela, Dept Radiotherapy, Santiago De Compostela, Spain

[9] Royal Marsden Hosp, Funct Imaging, Sutton, Surrey, England

来源：

CURRENT PROBLEMS IN DIAGNOSTIC RADIOLOGY | 2015年 / 44卷 / 05期

关键词：

D O I：

10.1067/j.cpradiol.2015.02.010

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Angiogenesis is a key cancer hallmark involved in tumor growth and metastasis development. Tumor angiogenesis is the process whereby new blood vessels are formed to supply nutrients and oxygen to support the growth of tumors. This article reviews the biological basis behind imaging features and the different imaging modalities used to assess the status of tumor neovasculature in vivo at different scales: structural, functional, and molecular. (C) 2015 Mosby, Inc. All rights reserved.

引用

页码：407 / 424

页数：18

共 67 条

[1] Recommendations for measurement of tumour vascularity with positron emission tomography in early phase clinical trials [J].

Aboagye, Eric O. ;

Gilbert, Fiona J. ;

Fleming, Ian N. ;

Beer, Ambros J. ;

Cunningham, Vincent J. ;

Marsden, Paul K. ;

Visvikis, Dimitris ;

Gee, Antony D. ;

Groves, Ashley M. ;

Kenny, Laura M. ;

Cook, Gary J. ;

Kinahan, Paul E. ;

Myers, Melvyn ;

Clarke, Larry .

EUROPEAN RADIOLOGY, 2012, 22 (07) :1465-1478

[2] Transcriptional Switch of Dormant Tumors to Fast-Growing Angiogenic Phenotype [J].

Almog, Nava ;

Ma, Lili ;

Raychowdhury, Raktima ;

Schwager, Christian ;

Erber, Ralf ;

Short, Sarah ;

Hlatky, Lynn ;

Vajkoczy, Peter ;

Huber, Peter E. ;

Folkman, Judah ;

Abdollahi, Amir .

CANCER RESEARCH, 2009, 69 (03) :836-844

[3] Imaging Key Biomarkers of Tumor Angiogenesis [J].

Backer, Marina V. ;

Backer, Joseph M. .

THERANOSTICS, 2012, 2 (05) :502-515

[4] The angiogenic switch in carcinogenesis [J].

Baeriswyl, Vanessa ;

Christofori, Gerhard .

SEMINARS IN CANCER BIOLOGY, 2009, 19 (05) :329-337

[5]

Baish JW, 2000, CANCER RES, V60, P3683

[6] Macromolecular MRI contrast agents for imaging tumor angiogenesis [J].

Barrett, Tristan ;

Kobayashi, Hisataka ;

Brechbiel, Martin ;

Choyke, Peter L. .

EUROPEAN JOURNAL OF RADIOLOGY, 2006, 60 (03) :353-366

[7] Multimodality molecular imaging of tumor angiogenesis [J].

Cai, Weibo ;

Chen, Xiaoyuan .

JOURNAL OF NUCLEAR MEDICINE, 2008, 49 :113S-128S

[8] Tumour vasculogenic mimicry is associated with poor prognosis of human cancer patients: A systemic review and meta-analysis [J].

Cao, Zhifei ;

Bao, Meimei ;

Miele, Lucio ;

Sarkar, Fazlul H. ;

Wang, Zhiwei ;

Zhou, Quansheng .

EUROPEAN JOURNAL OF CANCER, 2013, 49 (18) :3914-3923

[9] Molecular mechanisms and clinical applications of angiogenesis [J].

Carmeliet, Peter ;

Jain, Rakesh K. .

NATURE, 2011, 473 (7347) :298-307

[10] Ultrasound contrast agents:: properties, principles of action, tolerance, and artifacts [J].

Correas, JM ;

Bridal, L ;

Lesavre, A ;

Méjean, A ;

Claudon, M ;

Hélénon, O .

EUROPEAN RADIOLOGY, 2001, 11 (08) :1316-1328

← 1 2 3 4 5 6 7 →