STUDIES OF INHIBITION OF RAT SPERMIDINE SYNTHASE AND SPERMINE SYNTHASE

被引:109
作者
HIBASAMI, H
BORCHARDT, RT
CHEN, SY
COWARD, JK
PEGG, AE
机构
[1] PENN STATE UNIV,MILTON S HERSHEY MED CTR,DEPT PHYSIOL,HERSHEY,PA 17033
[2] YALE UNIV,SCH MED,DEPT PHARMACOL,NEW HAVEN,CT 06510
[3] UNIV KANSAS,DEPT BIOCHEM,LAWRENCE,KS 66045
[4] PENN STATE UNIV,MILTON S HERSHEY MED CTR,SPECIALIZED CANC RES CTR,HERSHEY,PA 17033
关键词
D O I
10.1042/bj1870419
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:419 / 428
页数:10
相关论文
共 44 条
[1]   AFFINITY LABELING OF HISTAMINE N-METHYLTRANSFERASE BY 2',3'-DIALDEHYDE DERIVATIVES OF S-ADENOSYLHOMOCYSTEINE AND S-ADENOSYLMETHIONINE - KINETICS OF INACTIVATION [J].
BORCHARDT, RT ;
WU, YS ;
WU, BS .
BIOCHEMISTRY, 1978, 17 (20) :4145-4153
[2]   S-ARISTEROMYCINYL-L-HOMOCYSTEINE, A POTENT INHIBITOR OF S-ADENOSYLMETHIONINE-DEPENDENT TRANSMETHYLATIONS [J].
BORCHARDT, RT ;
WU, YS .
JOURNAL OF MEDICINAL CHEMISTRY, 1976, 19 (01) :197-198
[3]   POTENTIAL INHIBITORS OF S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASES .7. ROLE OF RIBOSYL MOIETY IN ENZYMATIC BINDING OF S-ADENOSYL-L-HOMOCYSTEINE AND S-ADENOSYL-L-METHIONINE [J].
BORCHARDT, RT ;
WU, YS ;
WU, BS .
JOURNAL OF MEDICINAL CHEMISTRY, 1978, 21 (12) :1307-1310
[4]   POTENTIAL INHIBITORS OF S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASES .3. MODIFICATIONS OF SUGAR PORTION OF S-ADENOSYLHOMOCYSTEINE [J].
BORCHARDT, RT ;
WU, YS .
JOURNAL OF MEDICINAL CHEMISTRY, 1975, 18 (03) :300-304
[5]   POTENTIAL INHIBITORS OF S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASES .6. STRUCTURAL MODIFICATIONS OF S-ADENOSYLMETHIONINE [J].
BORCHARDT, RT ;
WU, YS ;
HUBER, JA ;
WYCPALEK, AF .
JOURNAL OF MEDICINAL CHEMISTRY, 1976, 19 (09) :1104-1110
[6]   POTENTIAL INHIBITORS OF S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASES .4. FURTHER MODIFICATIONS OF AMINO-ACID AND BASE PORTIONS OF S-ADENOSYL-L-HOMOCYSTEINE [J].
BORCHARDT, RT ;
HUBER, JA ;
WU, YS .
JOURNAL OF MEDICINAL CHEMISTRY, 1976, 19 (09) :1094-1099
[7]   POTENTIAL INHIBITORS OF S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASES .2. MODIFICATION OF BASE PORTION OF S-ADENOSYLHOMOCYSTEINE [J].
BORCHARDT, RT ;
HUBER, JA ;
WU, YS .
JOURNAL OF MEDICINAL CHEMISTRY, 1974, 17 (08) :868-873
[8]   POTENTIAL INHIBITORS OF S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASES .1. MODIFICATION OF AMINO-ACID PORTION OF S-ADENOSYLHOMOCYSTEINE [J].
BORCHARDT, RT ;
WU, YS .
JOURNAL OF MEDICINAL CHEMISTRY, 1974, 17 (08) :862-868
[9]  
Borchardt RT, 1977, BIOCH ADENOSYLMETHIO, P151
[10]  
BORCHARDT RT, 1979, TRANSMETHYLATION, P197