PROTEIN TURNOVER IN CELL-ENRICHED FRACTIONS FROM RABBIT BRAIN

被引：192

作者：

BLOMSTRAND, C

HAMBERGER, A

机构：

[1] Institute of Neurobiology, University of Göteborg, Goteborg

来源：

JOURNAL OF NEUROCHEMISTRY | 1969年 / 16卷 / 09期

关键词：

D O I：

10.1111/j.1471-4159.1969.tb05992.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Abstract— A modification of the available methods was used for preparation of nerve and glia cell‐enriched fractions from rabbit brain and spinal cord. The rate of incorporation of tritiated leucine and the turnover rates of protein during 10 days was studied in the bulkprepared cell fractions. The rate of incorporation into the nerve cell fraction was approximately three times greater than in the glia fraction. The nerve cells had one rapid and one slow phase in decline of radioactivity, while the glial cells were characterized by a more uniform decline. The soluble radioactivity was followed in whole tissue of brain and spinal cord and certain differences between the two were observed. Copyright © 1969, Wiley Blackwell. All rights reserved

引用

页码：1401 / +

页数：1

共 21 条

[1] REGIONAL UTILIZATION OF LEUCINE-H3 BY NORMAL RAT BRAIN - MICRODENSITOMETRIC EVALUATION OF AUTORADIOGRAMS [J].