B-Z CONFORMATIONAL TRANSITION AND HYDRATION OF POLY (DC-DG).POLY (DC-DG) IN FIBERS

被引：8
|
作者：
ALBISER, G
PREMILAT, S
机构：
[1] Laboratoire de Biophysique Moléculaire, UA CNRS 494, Faculté des Sciences, 54506 Vandoeuvre les Nancy
来源：
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | 1992年 / 14卷 / 03期
关键词：
POLY(DC-DG).POLY(DC-DG); B-Z HELICAL TRANSITION; HYDRATION; X-RAY DIFFRACTION; FIBER DIMENSIONS;
D O I：
10.1016/S0141-8130(05)80006-6
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The B-Z transition of poly(dC-dG).poly(dC-dG) has been studied by fibre X-ray diffraction and measurement of fibre dimensions. The polymorphism of the Z form is well observed as a function of variations of the r.h. (relative humidity). The Z to B transition is obtained at very high r.h. values. The cooperative transition from B to Z is associated with a disorganization of the fibre. Details about the hydration of the polynucleotide during conformational transitions are presented and it is shown that a nucleotide in Z form can be associated with up to 16 water molecules and up to 22 when in the B form.
引用
收藏
页码：161 / 165
页数：5
相关论文
共 50 条
  • [1] ETHYLATION OF POLY(DC-DG).POLY(DC-DG) BY ETHYL METHANESULFONATE STIMULATES THE ACTIVITY OF MAMMALIAN DNA METHYLTRANSFERASE INVITRO
    FARRANCE, IK
    IVARIE, R
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (04) : 1045 - 1049
  • [2] POLAROGRAPHIC INVESTIGATION OF THE B-Z TRANSITION OF POLY(DG-DC).POLY(DG-DC)
    SEQUARIS, JM
    KABA, ML
    VALENTA, P
    BIOELECTROCHEMISTRY AND BIOENERGETICS, 1984, 13 (1-3): : 225 - 227
  • [3] DC-DG ALTERNATING OLIGONUCLEOTIDES - THERMODYNAMIC AND KINETIC ASPECTS OF THE B-Z TRANSFORMATION
    MANZINI, G
    XODO, LE
    QUADRIFOGLIO, F
    VANBOOM, JH
    VANDERMAREL, GA
    JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 1987, 4 (04): : 651 - 662
  • [4] CONFORMATION AND DYNAMICS OF SHORT DNA DUPLEXES - (DC-DG)3 AND (DC-DG)4
    BORER, PN
    ZANATTA, N
    HOLAK, TA
    LEVY, GC
    VANBOOM, JH
    WANG, AHJ
    JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 1984, 1 (06): : 1373 - 1386
  • [5] B-Z TRANSITION IN POLY(DG-DC).POLY(DG-DC) IN THE PRESENCE OF FORMALDEHYDE AMINO DERIVATIVES
    POVERENNY, AM
    KISELEVA, VI
    TYAGLOV, BV
    PERMOGOROV, VI
    FEBS LETTERS, 1985, 186 (02) : 197 - 200
  • [6] CHANGES IN THE HELICAL REPEAT OF POLY(DG-M5DC).POLY(DG-M5DC) AND POLY(DG-DC).POLY(DG-DC) ASSOCIATED WITH THE B-Z TRANSITION
    BEHE, M
    ZIMMERMAN, S
    FELSENFELD, G
    NATURE, 1981, 293 (5829) : 233 - 235
  • [7] BASE PROTONATION FACILITATES THE SALT INDUCED B-Z TRANSITION OF POLY(DG-DC)-POLY(DG-DC)
    CHEN, FM
    BIOPHYSICAL JOURNAL, 1984, 45 (02) : A290 - A290
  • [8] B-Z transition in poly (dG-dC) in the presence of mitoxantrone
    Karapetyan, Armen T.
    Torosyan, Margairta A.
    Babayan, Yuri S.
    JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2015, 33 : 94 - 94
  • [9] Differential interactions of the Mg2+ complexes of chromomycin A(3) and mithramycin with poly(dG-dC)center dot poly(dC-dG) and poly(dG)center dot poly(dC)
    Majee, S
    Sen, R
    Guha, S
    Bhattacharyya, D
    Dasgupta, D
    BIOCHEMISTRY, 1997, 36 (08) : 2291 - 2299
  • [10] BASE PROTONATION FACILITATES B-Z INTERCONVERSIONS OF POLY(DG-DC).POLY(DG-DC)
    CHEN, FM
    BIOCHEMISTRY, 1984, 23 (25) : 6159 - 6165
12345