FATTY-ACID COMPOSITION OF CLINICALLY HEALTHY AND MALIGNANT ORAL EPITHELIUM

被引：5

作者：

MACLEOD, RI ^{[1
]}

CASSIDY, D ^{[1
]}

LAKER, MF ^{[1
]}

SOAMES, JV ^{[1
]}

机构：

[1] UNIV NEWCASTLE UPON TYNE,DEPT CLIN BIOCHEM,NEWCASTLE TYNE NE1 7RU,TYNE & WEAR,ENGLAND

来源：

JOURNAL OF ORAL PATHOLOGY & MEDICINE | 1990年 / 19卷 / 04期

关键词：

carcinoma; oral; fatty acids; mouth; epithelium;

D O I：

10.1111/j.1600-0714.1990.tb00814.x

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

The fatty acid composition of epithelium from clinically healthy oral mucosa and of oral squamous cell carcinoma was analyzed by gas/liquid chromatography following extraction using a modified Folch technique and conversion of fatty acids to methyl esters. There were significant reductions in the relative proportions of palmitoleic and oleic acids and elevation of the relative proportions of palmitic, stearic and arachidonic acids in samples from squamous cell carcinoma. These differences could reflect changes in cell membranes and/or fatty acid metabolism. Further studies are required to assess their functional, diagnostic and prognostic significance. Copyright © 1990, Wiley Blackwell. All rights reserved

引用

页码：149 / 151

页数：3