OXIDATION AND CLAISEN CONDENSATION PRODUCTS OF 3-NITRO-O-XYLENE

被引：14

作者：

ASKAM, V

DEEKS, RHL

机构：

[1] Welsh School of Pharmacy, University of Wales, Institute of Science and Technology, Cardiff CF1 3NU, Cathays Park

来源：

JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC | 1969年 / 14期

关键词：

D O I：

10.1039/j39690001935

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

When 3-nitro-o-xylene was oxidised with chromyl acetate, the methyl group remote from the nitro-group was attacked, yielding 2-methyl-3-nitrobenzylidene diacetate. The adjacent methyl group reacted with diethyl oxalate under the conditions of the Claisen condensation; oxidation of the product gave 2-methyl-6-nitrophenyl-acetic acid which, on reductive cyclisation, gave 4-methyloxindole.

引用

页码：1935 / &

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