INVITRO ACTIVITY OF HR 756, A NEW CEPHALOSPORIN, AGAINST NEISSERIA-GONORRHOEAE

被引:29
作者
MURRAY, PR [1 ]
CHRISTMAN, JL [1 ]
MEDOFF, G [1 ]
机构
[1] WASHINGTON UNIV,SCH MED,DIV INFECT DIS,ST LOUIS,MO 63110
关键词
D O I
10.1128/AAC.15.3.452
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The in vitro activity of HR 756 was compared with penicillin, cefamandole, cefoxitin, and tetracycline against Neisseria gonorrhoeae. A total of 192 randomly selected isolates (of which 23 had minimal inhibitory concentrations of ≥0.5 μg/ml for pencillin) and three β-lactamase-producing isolates were tested. HR 756 was the most active antibiotic tested, with more than 90% of the isolates inhibited by 0.008 μg/ml and all inhibited by 0.25 μ/ml.
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页码:452 / 454
页数:3
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