INVESTIGATION ON THE MORPHOLOGY AND PROPERTIES OF AGGREGATE STRUCTURES OF NATURAL PHOSPHOLIPIDS IN AQUEOUS SYSTEM USING CRYO-TEM

被引：7

作者：

Hudiyanti, Dwi ^{[1
,2
]}

Raharjo, Tri Joko ^{[2
]}

Narsito ^{[2
]}

Noegrohati, Sri ^{[3
]}

机构：

[1] Diponegoro Univ, Dept Chem, Jl Prof H Sudharto SH, Semarang 50275, Tembalang, Indonesia

[2] Univ Gadjah Mada, Fac Math & Nat Sci, Dept Chem, Yogyakarta 55281, Indonesia

[3] Univ Gadjah Mada, Fac Pharm, Yogyakarta 55281, Indonesia

来源：

INDONESIAN JOURNAL OF CHEMISTRY | 2012年 / 12卷 / 01期

关键词：

vesicle; liposome; Cryo-TEM; phospholipids; coconut; sesame seed; candle tree;

D O I：

10.22146/ijc.21372

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Cryogenic transmission electron microscopy (Cryo-TEM) was used to investigate the aggregates morphology and properties of candle tree (Aleurites moluccana) endosperm, sesame (Sesamum indicum L. syn.) seeds, and coconut (Cocos nucifera) endosperm phospholipids in dilute aqueous system. The micrographs showed that candle tree phospholipids formed planar bilayer and cluster of vesicles with lipid droplets, while coconut and sesame phospholipids formed well-defined unilamellar vesicles. The vesicles size could be as small as 50 nm in diameter. Coconut phospholipids also showed a good bending ability. Formation of clusters of vesicles was also found in coconut phospholipids dispersion, but this cluster was easily broken by extrusion through a small pore membrane.

引用

页码：57 / 61

页数：5

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