A PHARMACOKINETIC INTERACTION BETWEEN CIMETIDINE OR RANITIDINE AND LORNOXICAM

被引：7
|
作者：
RAVIC, M
SALASHERRERA, I
JOHNSTON, A
TURNER, P
FOLEY, K
ROSENOW, DE
机构：
[1] ST BARTHOLOMEWS HOSP,DEPT CLIN PHARMACOL,LONDON EC1A 7BE,ENGLAND
[2] CLIN & GEN LTD,ADVISORY SERV,LONDON W1N 2AA,ENGLAND
[3] HAFSLUND NYCOMED PHARMA AG,LINZ,AUSTRIA
来源：
POSTGRADUATE MEDICAL JOURNAL | 1993年 / 69卷 / 817期
关键词：
D O I：
10.1136/pgmj.69.817.865
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Cimetidine 400 mg twice daily significantly increased serum concentrations and reduced apparent oral clearance of lornoxicam 8 mg twice daily in 12 healthy volunteers. Ranitidine 150 mg twice daily produced no significant changes in lornoxicam pharmacokinetics.
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页码：865 / 866
页数：2
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