LIQUID-CHROMATOGRAPHIC RESOLUTION OF ENANTIOMERS ON CHIRAL AMIDE BONDED SILICA GEL NORMAL PHASE - SEPARATION OF RACEMIC ALPHA-AMINO-ACID DERIVATIVES BY N-ACETYL-L-VALYL-AMINOPROPYL-SILANIZED SILICA (AVA) PHASE

被引：27

作者：

HARA, S

DOBASHI, A

机构：

[1] Tokyo College of Pharmacy, Tokyo 192-03, Hachioji

来源：

JOURNAL OF LIQUID CHROMATOGRAPHY | 1979年 / 2卷 / 06期

关键词：

D O I：

10.1080/01483917908060111

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A new optically active stationary phase obtained by grafting N-acetyl-L-valine with 3-aminopropylsilanized silica was developed. The high-efficiency chiral column was prepared by slurry packing procedure. Direct resolution of the racemates of a-amino acid derivatives was accomplished by using normal phase liquid chromatography. Copyright © 1979, Taylor & Francis Group, LLC. All rights reserved.

引用

页码：883 / 889

页数：7

共 5 条

[1] LIGAND-EXCHANGE CHROMATOGRAPHY OF RACEMATES .6. SEPARATION OF OPTICAL ISOMERS OF AMINO-ACIDS ON POLYSTYRENE RESINS CONTAINING L-PROLINE OR L-AZETIDINE CARBOXYLIC-ACID [J].