CLONED FRAGMENTS OF THE PLASMID COLV,I-K94 SPECIFYING VIRULENCE AND SERUM RESISTANCE

被引：183

作者：

BINNS, MM

DAVIES, DL

HARDY, KG

机构：

[1] Biological Laboratory, University of Kent at Canterbury, Canterbury

来源：

NATURE | 1979年 / 279卷 / 5716期

关键词：

D O I：

10.1038/279778a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

A cloned BamH1-generated fragment of ColV,I-K94 increased the virulence of Escherichia coli, causing an approximately 100-fold reduction in LD50 for chicks. A genetic determinant f or resistance to the bactericidal effects of serum was mapped to a 5,300 base-pair sequence within the fragment. Neither colicin V nor immunity to colicin V affected the pathogenicity of E. coli for chicks. © 1979 Nature Publishing Group.

引用

页码：778 / 781

页数：4

共 38 条

[1] CIRCULAR DNA FORMS OF COLICINOGENIC FACTORS E1 E2 AND E3 FROM ESCHERICHIA COLI [J].