A SINGLE-BASE CHANGE AT A SPLICE SITE IN A BETA-0-THALASSEMIC GENE CAUSES ABNORMAL RNA SPLICING

被引：326
作者：
TREISMAN, R
PROUDFOOT, NJ
SHANDER, M
MANIATIS, T
机构：
来源：
CELL | 1982年 / 29卷 / 03期
关键词：
D O I：
10.1016/0092-8674(82)90452-4
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：903 / 911
页数：9
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共 44 条
[1]  
AVVEDIMENTO E, 1980, CELL, V21, P689
[2]   A NUCLEOTIDE CHANGE AT A SPLICE JUNCTION IN THE HUMAN BETA-GLOBIN GENE IS ASSOCIATED WITH BETAO-THALASSEMIA [J].
BAIRD, M ;
DRISCOLL, C ;
SCHREINER, H ;
SCIARRATTA, GV ;
SANSONE, G ;
NIAZI, G ;
RAMIREZ, F ;
BANK, A .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1981, 78 (07) :4218-4221
[3]   EXPRESSION OF A BETA-GLOBIN GENE IS ENHANCED BY REMOTE SV40 DNA-SEQUENCES [J].
BANERJI, J ;
RUSCONI, S ;
SCHAFFNER, W .
CELL, 1981, 27 (02) :299-308
[4]  
BENZ EJ, 1981, BLOOD S, V58, pA52
[5]   SIZING AND MAPPING OF EARLY ADENOVIRUS MESSENGER-RNAS BY GEL-ELECTROPHORESIS OF S1 ENDONUCLEASE-DIGESTED HYBRIDS [J].
BERK, AJ ;
SHARP, PA .
CELL, 1977, 12 (03) :721-732
[6]   OVALBUMIN GENE - EVIDENCE FOR A LEADER SEQUENCE IN MESSENGER-RNA AND DNA SEQUENCES AT EXON-INTRON BOUNDARIES [J].
BREATHNACH, R ;
BENOIST, C ;
OHARE, K ;
GANNON, F ;
CHAMBON, P .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1978, 75 (10) :4853-4857
[7]   BETA+ THALASSEMIA - ABERRANT SPLICING RESULTS FROM A SINGLE POINT MUTATION IN AN INTRON [J].
BUSSLINGER, M ;
MOSCHONAS, N ;
FLAVELL, RA .
CELL, 1981, 27 (02) :289-298
[8]   BETA-O THALASSEMIA, A NONSENSE MUTATION IN MAN [J].
CHANG, JC ;
WAIKAN, Y .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1979, 76 (06) :2886-2889
[9]   SUPPRESSION OF THE NONSENSE MUTATION IN HOMOZYGOUS BETA-O-THALASSEMIA [J].
CHANG, JC ;
TEMPLE, GF ;
TRECARTIN, RF ;
KAN, YW .
NATURE, 1979, 281 (5732) :602-603
[10]   RNA SPLICING GENERATES A VARIANT LIGHT CHAIN FROM AN ABERRANTLY REARRANGED K-GENE [J].
CHOI, E ;
KUEHL, M ;
WALL, R .
NATURE, 1980, 286 (5775) :776-779
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