CA2+-DEPENDENT CARBOHYDRATE-RECOGNITION DOMAINS IN ANIMAL PROTEINS

被引：222
作者：
DRICKAMER, K
机构：
[1] Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032
来源：
CURRENT OPINION IN STRUCTURAL BIOLOGY | 1993年 / 3卷 / 03期
关键词：
D O I：
10.1016/S0959-440X(05)80112-5
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Many Ca2+-dependent (C-type) animal lectins contain a common sequence motif, with 14 invariant and 18 highly conserved residues distributed over discrete carbohydrate-recognition domains of 115-130 amino acids. Domains that display the C-type carbohydrate-recognition domain motif are found in an increasing number of proteins, although only some are known to bind carbohydrate. Progress is being made towards making deductions about the structure and activity of these domains from their sequences.
引用
收藏
页码：393 / 400
页数：8
相关论文
共 56 条
[1]   EVIDENCE FOR 2 CLASSES OF CARBOHYDRATE BINDING-SITES ON SELECTINS [J].
ASA, D ;
GANT, T ;
ODA, Y ;
BRANDLEY, BK .
GLYCOBIOLOGY, 1992, 2 (05) :395-399
[2]  
ATODA H, 1991, J BIOL CHEM, V266, P14903
[3]   CD21 IS A LIGAND FOR CD23 AND REGULATES IGE PRODUCTION [J].
AUBRY, JP ;
POCHON, S ;
GRABER, P ;
JANSEN, KU ;
BONNEFOY, JY .
NATURE, 1992, 358 (6386) :505-507
[4]  
BETTLER B, 1992, J BIOL CHEM, V267, P185
[5]  
BEZOUSKA K, 1991, J BIOL CHEM, V266, P11604
[6]  
CHAN PY, 1989, J IMMUNOL, V142, P1727
[7]   SEQUENCE AND EXPRESSION OF A MEMBRANE-ASSOCIATED C-TYPE LECTIN THAT EXHIBITS CD4-INDEPENDENT BINDING OF HUMAN-IMMUNODEFICIENCY-VIRUS ENVELOPE GLYCOPROTEIN-GP120 [J].
CURTIS, BM ;
SCHARNOWSKE, S ;
WATSON, AJ .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (17) :8356-8360
[8]   ENHANCED EXPRESSION OF AN EXOCRINE PANCREATIC PROTEIN IN ALZHEIMERS-DISEASE AND THE DEVELOPING HUMAN BRAIN [J].
DELAMONTE, SM ;
OZTURK, M ;
WANDS, JR .
JOURNAL OF CLINICAL INVESTIGATION, 1990, 86 (03) :1004-1013
[9]  
DOEGE KJ, 1991, J BIOL CHEM, V266, P894
[10]  
DRICKAMER K, 1988, J BIOL CHEM, V263, P9557
123456