EFFECT OF SATURABLE BINDING ON THE PHARMACOKINETICS OF DRUGS - A SIMULATION

[1] ANTON AH, 1960, J PHARMACOL EXP THER, V129, P282

[2] SERUM CONCENTRATIONS OF FREE DIPHENYLHYDANTOIN AND THEIR RELATIONSHIP TO CLINICAL INTOXICATION [J]. EPILEPSIA, 1973, 14 (02) : 177 - 184

[3] CASTLEMAN PA, 1974, NATL COMPUT C EXPOSI, V43, P457

[4] NUMERICAL SOLUTION OF NONLINEAR PHARMACOKINETIC EQUATIONS - EFFECTS OF PLASMA PROTEIN BINDING ON DRUG DISTRIBUTION AND ELIMINATION [J]. JOURNAL OF PHARMACEUTICAL SCIENCES, 1971, 60 (11) : 1623 - +

[5] GIBALDI M, 1978, CLIN PHARMACOL THER, V24, P1

[6] APPARENT VOLUMES OF DISTRIBUTION AND DRUG BINDING TO PLASMA-PROTEINS AND TISSUES [J]. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 1978, 13 (05) : 373 - 378

[7] GUYTON AC, 1976, TXB MED PHYSL, P424

[8] PLASMA AND TISSUE PROTEIN-BINDING OF DRUGS IN PHARMACOKINETICS [J]. DRUG METABOLISM REVIEWS, 1976, 5 (01) : 43 - 140

[9] KRUEGERTHIEMER E, 1965, ANTIMICROB AGENTS CH, V5, P183

[10] INFLUENCE OF BINDING ON PHARMACOLOGIC ACTIVITY OF ANTIBIOTICS [J]. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1973, 226 (NOV26) : 214 - 224

[1] ANTON AH, 1960, J PHARMACOL EXP THER, V129, P282

[2] SERUM CONCENTRATIONS OF FREE DIPHENYLHYDANTOIN AND THEIR RELATIONSHIP TO CLINICAL INTOXICATION [J]. EPILEPSIA, 1973, 14 (02) : 177 - 184

[3] CASTLEMAN PA, 1974, NATL COMPUT C EXPOSI, V43, P457

[4] NUMERICAL SOLUTION OF NONLINEAR PHARMACOKINETIC EQUATIONS - EFFECTS OF PLASMA PROTEIN BINDING ON DRUG DISTRIBUTION AND ELIMINATION [J]. JOURNAL OF PHARMACEUTICAL SCIENCES, 1971, 60 (11) : 1623 - +

[5] GIBALDI M, 1978, CLIN PHARMACOL THER, V24, P1

[6] APPARENT VOLUMES OF DISTRIBUTION AND DRUG BINDING TO PLASMA-PROTEINS AND TISSUES [J]. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 1978, 13 (05) : 373 - 378

[7] GUYTON AC, 1976, TXB MED PHYSL, P424

[8] PLASMA AND TISSUE PROTEIN-BINDING OF DRUGS IN PHARMACOKINETICS [J]. DRUG METABOLISM REVIEWS, 1976, 5 (01) : 43 - 140

[9] KRUEGERTHIEMER E, 1965, ANTIMICROB AGENTS CH, V5, P183

[10] INFLUENCE OF BINDING ON PHARMACOLOGIC ACTIVITY OF ANTIBIOTICS [J]. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1973, 226 (NOV26) : 214 - 224