Synthesis and Antimicrobial activity of some new Pyrimidines of 6-chlorobenzimidazoles

被引：2

作者：

Madawali, Indira M. ^{[1
]}

Kalyane, Navanath, V ^{[1
]}

Gaviraj, E. N. ^{[1
]}

Shivakumar, B. ^{[1
]}

机构：

[1] BLDEAs SSM Coll Pharm & Res Ctr, Dept Pharmaceut Chem, Vijayapur 586103, Karnataka, India

来源：

ORIENTAL JOURNAL OF CHEMISTRY | 2018年 / 34卷 / 03期

关键词：

Benzimidazoles; Chalcones; Pyrimidines; Antimicrobial activity;

D O I：

10.13005/ojc/340358

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A new series of pyrimidines of 6-chlorobenzimidazoles have been synthesized by the reaction of chalcone derivatives of 6-chlorobenzimidazole with guanidine nitrate in ethanol and aqueous solution of sodium hydroxide for evaluating them as potent antimicrobial agents. Results reveal that, compounds exhibited significant antibacterial and antifungal activities.

引用

页码：1633 / 1637

页数：5

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