QUANTITATION OF OXYPURINES AND ALLOPURINOL METABOLITES IN BIOLOGICAL FLUIDS BY CATION-EXCHANGE CHROMATOGRAPHY

被引：26
作者：
SWEETMAN, L
NYHAN, WL
机构：
[1] Department of Pediatrics, University of Miami School of Medicine, Miami
来源：
ANALYTICAL BIOCHEMISTRY | 1969年 / 31卷 / 1-3期
基金：
美国国家卫生研究院;
关键词：
D O I：
10.1016/0003-2697(69)90276-0
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Chromatography of urine, cerebrospinal fluid, and deproteinized serum on 30 × 0.9 cm columns of AG 50 permits the convenient separation of hypoxanthine, xanthine, allopurinol, and its metabolites. Quantitation by determination of absorbance at 250 mμ is accurate and can be automated. Column preparation is simple, and the columns can be regenerated and used daily for several months with no loss of resolution. © 1969.
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页码：358 / &
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