STUDIES OF SELENIUM SUPPLEMENTATION WITH INORGANIC AND COMBINED INORGANIC-ORGANIC SE IN HUMANS

被引：0

作者：

JOHANSSON, E ^{[1
]}

WESTERMARCK, T ^{[1
]}

机构：

[1] HELSINKI CENT INST MENTALLY RETARDED, SF-02400 KIRKONUMMI, FINLAND

来源：

JOURNAL OF TRACE ELEMENTS AND ELECTROLYTES IN HEALTH AND DISEASE | 1993年 / 7卷 / 02期

关键词：

HUMAN; SELENIUM SUPPLEMENTATION; SODIUM SELENITE; L-SELENOMETHIONINE;

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

One hundred mug selenium as sodium selenite alone or 50 mug selenium as selenite and 50 mug selenium as L-selenomethionine along with vitamin E, vitamins B2, B-6 and B-12 were given to two groups of 7 persons/group of healthy volunteers for 4 months. The combination of sodium selenite and L-selenomethionine along with vitamins, Metselen gave significant higher concentration of plasma Se than sodium selenite alone. The concentration of erythrocyte Se was also significantly higher by supplementation with Metselen than that of sodium selenite alone. The group given Metselen showed significantly higher activity of E-GSH-Px than the group given sodium selenite. One month after stopping the supplementation urinary selenium (24h) of Metselen and sodium selenite returned to original values. The combination of sodium selenite, L-selenomethionine along with vitamins was more effective than sodium selenite alone.

引用

页码：113 / 114

页数：2

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