EFFECT OF LACTIC-ACID ON WATER-CONTENT AND OSMOTIC FRAGILITY OF ERYTHROCYTES IN-VITRO

被引：0

作者：

KOGAWA, H

SATOH, M

HIGUCHI, T

FUJIIKIYOSUE, A

SAHARA, T

KAGEYAMA, K

机构：

[1] OSAKA CITY UNIV,SCH MED,DEPT LEGAL MED,OSAKA 545,JAPAN

[2] OSAKA CITY UNIV,SCH MED,DIV RADIOL TECHNOL,OSAKA 545,JAPAN

[3] OSAKA CITY UNIV,SCH MED,CTR RADIOISOTOPE,OSAKA 545,JAPAN

来源：

CELLULAR AND MOLECULAR BIOLOGY | 1995年 / 41卷 / 06期

关键词：

ERYTHROCYTE; WATER CONTENT; OSMOTIC FRAGILITY; LACTIC ACID; HYPERTHERMIA;

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Effects of lactic acid in red blood cells on osmotic fragility and water content of erythrocytes after hyperthermia were investigated. The osmotic fragility of erythrocytes increased following one-hour incubation with the addition of lactic acid at both 37 degrees C and 42 degrees C and that also increased after heating in vitro at 42 degrees C compared with those incubated at 37 degrees C, whether the lactic acid was added or not. The water content increased with the addition of lactic acid after heating in vitro at 42 degrees C. A high concentration of lactic acid and hyperthermia seem to cause the increase of intracellular water and the decrease of osmotic resistance of the red blood cells.

引用

页码：809 / 812

页数：4

共 12 条

[1]

BERNARD JF, 1975, NOUV PRESSE MED, V4, P1117

[2] HYPERTHERMIA, NA+K+ ATPASE AND LACTIC-ACID PRODUCTION IN SOME HUMAN-TUMOR CELLS [J].