Recent research on the factors governing resistance development among arthropod natural enemies is reviewed, including selection studies of resistance development in the predatory mite Amblyseius fallacis (Garman) and Tetranychus urticaeKoch and patterns of toxicity to pesticides and mixed function oxidase activity in a group of pests, predators and parasites. New areas of resistance development in the species Phytoseiulus persimilis A. H. and Typhlodromus pyriScheuten are discussed as are genetic studies of resistance in P. persimilis and the toxicology of resistance in A. fallacis. Lastly, the widespread documentation of resistance in A. fallacis, a predator of plant-feeding mites, the cecidomyid Aphidoletes aphidimyza (Rond.), a predator of aphids and 2 parasites of leafhopper in orchards of North America, is discussed relative to the long-term use of organophosphate-based insecticides and programs of integrated pest control. © 1979 Le François.