HEPARIN SURFACE-TREATMENT OF POLY(METHYLMETHACRYLATE) ALTERS ADHESION OF A STAPHYLOCOCCUS-AUREUS STRAIN - UTILITY OF BACTERIAL FATTY-ACID ANALYSIS

被引：46

作者：

ARCIOLA, CR ^{[1
]}

RADIN, L ^{[1
]}

ALVERGNA, P ^{[1
]}

CENNI, E ^{[1
]}

PIZZOFERRATO, A ^{[1
]}

机构：

[1] UNIV GENOA,INST MICROBIOL,I-16132 GENOA,ITALY

来源：

BIOMATERIALS | 1993年 / 14卷 / 15期

关键词：

BACTERIAL ADHESION; POLY(METHYLMETHACRYLATE); HEPARINIZATION; FATTY ACID METHYL ESTERS;

D O I：

10.1016/0142-9612(93)90161-T

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Bacterial adhesion on biomaterials is an important cause of associated infection. Many authors have studied the adhesion mechanisms of bacteria on biomaterials. These studies were useful in making materials more and more refractory to bacterial adhesion. We analysed the gas chromatographic modifications of structural fatty acids of a Staphylococcus aureus strain after adhesion on two polymers, poly(methylmethacrylate) (PMMA), whose biological compatibility is known, and heparin-surface-modified PMMA (HSM-PMMA). We noted changes to the chromatographic peaks peculiar to the fatty acids of S. aureus for each tested material and particularly for HSM-PMMA.

引用

页码：1161 / 1164

页数：4

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