CELL-SURFACE GLYCOPROTEIN ANALYSIS - DIAGNOSTIC TOOL IN HUMAN LEUKEMIAS

被引：50
作者：
ANDERSSON, LC
GAHMBERG, CG
SIIMES, MA
TEERENHOVI, L
VUOPIO, P
机构：
[1] UNIV HELSINKI, DEPT BACTERIOL & IMMUNOL, SF-00290 HELSINKI 29, FINLAND
[2] UNIV HELSINKI, CENT HOSP, DEPT MED 3, SF-00290 HELSINKI 29, FINLAND
[3] CHILDRENS HOSP, HELSINKI, FINLAND
来源：
INTERNATIONAL JOURNAL OF CANCER | 1979年 / 23卷 / 03期
关键词：
D O I：
10.1002/ijc.2910230306
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
We have radiolabelled surface glycoproteins of different types of leukemic cell. The labelled proteins were separated by polyacrylamide slab gel electrophoresis and visualized by fluorography. Surface glycoprotein patterns discriminatory for acute lymphocytic leukemia (ALL), chronic lymphocytic leukemia (CLL). acute myeloid leukemia (AML) and chronic myeloid leukemia (CML) were found. We conclude that the analysis of the surface glycoprotein profile provides a useful method for the classification of leukemic cells according to cell type and stage of differentiation. Copyright © 1979 Wiley‐Liss, Inc., A Wiley Company
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页码：306 / 311
页数：6
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