A BETA-LACTAMASE FROM SERRATIA-MARCESCENS HYDROLYZING THE 2-CARBOXYPENAM T-5575

被引：6
作者：
MATSUMURA, N
MITSUHASHI, S
机构：
[1] Episome Institute, Seta-gun, Gunma 371-01, 2220 Kogure, Fujimi-mura
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1995年 / 39卷 / 09期
关键词：
D O I：
10.1128/AAC.39.9.2132
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
A beta-lactamase was purified from Serratia marcescens GN16694; it hydrolyzed T-5575 and oxime-type cephalosporins, ie., cefuroxime and ceftazidime. Its isoelectric point and molecular weight were 8.6 and 42,000 respectively. This enzyme was not inhibited by EDTA and clavulanic acid. This enzyme is an unusual beta-lactamase and has been classified as a group 1 cephalosporinase.
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页码：2132 / 2134
页数：3
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