Palladium-Catalysed Coupling and Acid-Mediated Cyclisation: Synthesis of Fluorenones and Fluorenes

被引：4
|
作者：
Kumar, Devarapalli Ravi [1 ]
Kishore, Dakoju Ravi [1 ]
Satyanarayana, Gedu [1 ]
机构：
[1] Indian Inst Technol Hyderabad, Dept Chem, Sangareddy 502285, Telangana, India
来源：
SYNOPEN | 2018年 / 2卷 / 04期
关键词：
Friedel-Crafts; cyclocarbonylation; fluorenone; fluorine;
D O I：
10.1055/s-0037-1610663
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Palladium-catalysed sequential one-pot synthesis of fluorenones is described. The reaction comprises intermolecular Suzuki coupling and intramolecular acid-mediated cyclisation in a one-pot procedure. The protocol is also applied to the synthesis of fluorenes using a single column purification.
引用
收藏
页码：268 / 275
页数：8
相关论文
共 50 条
  • [1] Triflic acid-Mediated Expedient Synthesis of Benzo[a]fluorenes and Fluorescent Benzo[a]fluorenones
    Mandal, Mou
    Balamurugan, Rengarajan
    ADVANCED SYNTHESIS & CATALYSIS, 2018, 360 (07) : 1453 - 1465
  • [2] PALLADIUM-CATALYSED SYNTHESIS OF AROMATIC COUPLING COMPOUNDS
    ITATANI, H
    YOSHIMOTO, H
    CHEMISTRY & INDUSTRY, 1971, (24) : 674 - +
  • [3] Synthesis of fused tetracyclic spiroindoles via palladium-catalysed cascade cyclisation
    Iwata, Akira
    Inuki, Shinsuke
    Oishi, Shinya
    Fujii, Nobutaka
    Ohno, Hiroaki
    CHEMICAL COMMUNICATIONS, 2014, 50 (03) : 298 - 300
  • [4] Palladium-Catalysed Cyclisation of α-Hydroxy Allylic Acetates: A Formal Synthesis of (±)-Swainsonine
    Bates, Roderick W.
    Dewey, Mark R.
    Tang, Chi H.
    Safii, Shahidah Bte
    Hong, Yanhan
    Hsieh, Jolyn Ke Hui
    Siah, Pei Shan
    SYNLETT, 2011, (14) : 2053 - 2055
  • [5] Palladium-Catalysed Coupling Reactions
    de Vries, Johannes G.
    ORGANOMETALLICS AS CATALYSTS IN THE FINE CHEMICAL INDUSTRY, 2012, 42 : 1 - 34
  • [6] Palladium-Catalysed Cyclisation of N-Alkynyl Aminomalonates
    Hess, Wilfried
    Burton, Jonathan W.
    CHEMISTRY-A EUROPEAN JOURNAL, 2010, 16 (41) : 12303 - 12306
  • [7] Straightforward Synthesis of Isoellipticine by Palladium-Catalysed Coupling Reactions
    Naciuk, Fabricio F.
    Castro, Joaquim A. M.
    Serikava, Bruno K.
    Miranda, Paulo C. M. L.
    CHEMISTRYSELECT, 2018, 3 (02): : 436 - 439
  • [8] Palladium-catalysed cyclisation of alkenols: Synthesis of oxaheterocycles as core intermediates of natural compounds
    Palik, Miroslav
    Kozisek, Jozef
    Koos, Peter
    Gracza, Tibor
    BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, 2014, 10 : 2077 - 2086
  • [9] Palladium-Catalysed Cross-Coupling Reactions for the Synthesis of Chalcones
    Rullah, Kamal
    Aluwi, Mohd Fadhlizil Fasihi Mohd
    Yamin, Bohari M.
    Juan, Joon Ching
    Wai, Lam Kok
    ASIAN JOURNAL OF ORGANIC CHEMISTRY, 2019, 8 (08) : 1174 - 1193
  • [10] Palladium-catalysed synthesis of pyrimidines
    Ingebrigtsen, T
    Helland, I
    Lejon, T
    HETEROCYCLES, 2005, 65 (11) : 2593 - 2603
12345