THE VALDIVONES, ANTIINFLAMMATORY DITERPENE ESTERS FROM THE SOUTH-AFRICAN SOFT CORAL ALCYONIUM-VALDIVAE

被引：47

作者：

LIN, YC ^{[1
]}

BEWLEY, CA ^{[1
]}

FAULKNER, DJ ^{[1
]}

机构：

[1] UNIV CALIF SAN DIEGO,SCRIPPS INST OCEANOG,LA JOLLA,CA 92093

来源：

TETRAHEDRON | 1993年 / 49卷 / 36期

关键词：

D O I：

10.1016/S0040-4020(01)88021-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The South African soft coral Alcyonium valdivae contains five diterpene esters, valdivones A (1) and B (2), the corresponding methoxy ketals (3) and (4), and dihydrovaldivone A (5). Although the producing organisms are unrelated taxonomically, the valdivones are most closely related to the sarcodictins (e.g. 6) from the stoloniferan coral Sarcodictyon roseum. Valdivones A (1) and B (2) inhibit chemically-induced inflammation in the mouse ear assay.

引用

页码：7977 / 7984

页数：8

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