CELL-INTERACTIONS LEADING TO KIDNEY TUBULE DETERMINATION ARE TUNICAMYCIN SENSITIVE

被引：34

作者：

EKBLOM, P ^{[1
]}

NORDLING, S ^{[1
]}

SAXEN, L ^{[1
]}

RASILO, ML ^{[1
]}

RENKONEN, O ^{[1
]}

机构：

[1] UNIV HELSINKI,DEPT BIOCHEM,SF-00290 HELSINKI 29,FINLAND

来源：

CELL DIFFERENTIATION | 1979年 / 8卷 / 05期

关键词：

D O I：

10.1016/0045-6039(79)90019-8

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Induction of metanephric tubules in a transfilter model system is blocked by tunicamycin, an inhibitor of protein glycosylation. Tunicamycin did not affect protein synthesis, cell viability or ingrowth of cell processes into filter pores. Tunicamycin was found to decrease protein glycosylation and nucleic acid synthesis. The decreased protein glycosylation seems to correlate with the inhibitory effect on induction. © 1979.

引用

页码：347 / 352

页数：6

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