CALCIUM-BINDING INDUCES CONFORMATIONAL-CHANGES IN MUSCLE REGULATORY PROTEINS

被引：108
作者：
DASILVA, ACR
REINACH, FC
机构：
[1] A.C.R. da Silva and F.C. Reinach are, the Departamento de Bioquimica, Instituto de Quimica, CEP 01498 Sao Paulo, SP
来源：
TRENDS IN BIOCHEMICAL SCIENCES | 1991年 / 16卷 / 02期
基金：
巴西圣保罗研究基金会;
关键词：
D O I：
10.1016/0968-0004(91)90024-P
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Calcium binding to proteins containing the 'EF-hand' structural motif regulates a variety of biochemical processes including muscle contraction. Techniques such as protein crystallography, site-directed mutagenesis and domain transplantation experiments are being used to unravel the conformational changes induced by calcium binding.
引用
收藏
页码：53 / 57
页数：5
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