Pulmonary Fibrosis Under Chemotherapy with Oxaliplatin, 5-fluorouracil, and Leucovorin

被引：0

作者：

Jung, Jin Yong ^{[1
]}

Hur, Gyu Young ^{[1
]}

Jung, Ki Hwan ^{[1
]}

Jung, Hae Chul ^{[1
]}

Lee, Sung Yong ^{[1
]}

Choi, In Keun ^{[1
]}

Lee, Sang Yeub ^{[1
]}

Kim, Je Hyeong ^{[1
]}

Seo, Jae Hong ^{[1
]}

Shin, Chol ^{[1
]}

Shim, Jae Jeong ^{[1
]}

In, Kwang Ho ^{[1
]}

Kang, Kyung Ho ^{[1
]}

Yoo, Se Hwa ^{[1
]}

机构：

[1] Korea Univ, Coll Med, Dept Internal Med, Seoul, South Korea

来源：

TUBERCULOSIS AND RESPIRATORY DISEASES | 2005年 / 59卷 / 05期

关键词：

Oxaliplatin; Fluorouracil; Leucovorin; Chemotherapy; Pulmonary fibrosis;

D O I：

10.4046/trd.2005.59.5.536

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

The combination of oxaliplatin, 5-fluorouracil and leucovorin (FOLFOX) has recently been shown to be beneficial in advanced colorectal and gastric cancers. The side effects of this regimen include neutropenia, diarrhea and neurosensory toxicity. However, case reports on the pulmonary toxicities of this regimen are very limited. Especially, the development of pulmonary fibrosis has never been cited in the literature. Herein is reported the case of a patient treated with oxaliplatin, 5-fluorouracil and leucovorin combination chemotherapy in whom pulmonary fibrosis developed, but which improved after steroid pulse therapy.

引用

页码：536 / 540

页数：5

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