SELECTED BIOLOGICAL-ACTIVITIES OF SARAINES

被引：37
作者：
CAPRIOLI, V
CIMINO, G
DEGIULIO, A
MADAIO, A
SCOGNAMIGLIO, G
TRIVELLONE, E
机构：
[1] CNR,IST CHIM MOLEC INTERESSE BIOL,VIA TOIANO 6,I-80072 ARCO,ITALY
[2] AGRIMONT R&D,I-28100 NOVARA,ITALY
来源：
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY | 1992年 / 103卷 / 01期
关键词：
D O I：
10.1016/0305-0491(92)90447-Y
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
1. The Mediterranean sponge Reniera sarai, Pulitzeri-Finali, 1969 (Demospongiae: Haploscleridae: Renieridae) possesses in large amounts a series of unprecedented polycyclic alkaloids, saraines 1 -3 and saraines A-C. 2. The structural peculiarities of saraines, their chemical physical characteristics, along with their relevant abundance in the sponge, prompted a study aimed at investigating their biological properties. 3. Saraines were assayed for their cytotoxic, antibacterial, insecticidal and potential antitumoral activities. These results, along with the growth inhibition of fertilized sea urchin eggs, are reported.
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页码：293 / 296
页数：4
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