THE INFLUENCE OF GENETIC SEX ON SEXUAL-DIFFERENTIATION OF DIENCEPHALIC DOPAMINERGIC-NEURONS INVITRO AND INVIVO

被引:33
作者
KOLBINGER, W
TREPEL, M
BEYER, C
PILGRIM, C
REISERT, I
机构
[1] Abteilung für Anatomie, Zellbiologie der Universität Ulm, Ulm
关键词
SEXUAL DIFFERENTIATION; DOPAMINE; HYPOTHALAMUS; MORPHOMETRY;
D O I
10.1016/0006-8993(91)90079-B
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Soma sizes of embryonic male and female tyrosine hydroxylase-immunoreactive neurons were measured in 3 diencephalic regions in situ and in diencephalic dissociated cell cultures. Male neurons were about 30% larger than female neurons both in vitro and in situ. Treatment of cultures with sex steroids did not affect the sex differences. It is concluded that sexual differentiation of dopaminergic neurons may be under primary genetic control.
引用
收藏
页码:349 / 352
页数:4
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