VIRALLY INDUCED IMMUNOSUPPRESSION

被引：22
作者：
ZINKERNAGEL, RM
HENGARTNER, H
机构：
[1] University of Zurich, Zurich
来源：
CURRENT OPINION IN IMMUNOLOGY | 1992年 / 4卷 / 04期
关键词：
D O I：
10.1016/S0952-7915(06)80031-2
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
A mouse model of virus-triggered, T-cell mediated acquired immunosuppression is analyzed. Lymphocytic choriomeningitis virus initially infects mostly macrophages and antigen-presenting cells; these are destroyed by lymphocytic choriomeningitis virus specific cyotoxic T cells resulting in immunosupression. Similar immunopathological mechanisms may play a role in acquired immune deficiency syndrome.
引用
收藏
页码：408 / 412
页数：5
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