Recurrent ovarian Sertoli-Leydig cell tumor in a child with Peutz-Jeghers syndrome

被引：6

作者：

Bellfield, Edward J. ^{[1
]}

Alemzadeh, Ramin ^{[2
,3
]}

机构：

[1] Univ Illinois, Coll Med, Div Pediat Endocrinol, MC 856,840 South Wood St,CSN 330, Chicago, IL 60612 USA

[2] Univ Tennessee, Hlth Sci Ctr, Div Pediat Endocrinol, Memphis, TN 38103 USA

[3] Le Bonheur Childrens Hosp, Memphis, TN 38103 USA

来源：

OXFORD MEDICAL CASE REPORTS | 2016年 / 08期

关键词：

D O I：

10.1093/omcr/omw048

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We present a female child with Peutz-Jeghers syndrome (PJS) with a recurrent ovarian Sertoli-Leydig cell tumor (SLCT). SLCTs are relatively rare sex cord neoplasms that can occur in PJS. The patient was an African-American female who first presented at the age of 3 years with precocious puberty, and then at the age of 17 years with abdominal pain and irregular menses. In each case, she had resection of the mass, which included oophorectomy. To our knowledge, this is the first reported case in a child with PJS to have a recurrent ovarian SLCT.

引用

页码：186 / 189

页数：4

共 10 条

[1] High proportion of large genomic STK11 deletions in Peutz-Jeghers syndrome [J].

Aretz, S ;

Stienen, D ;

Uhlhaas, S ;

Loff, S ;

Back, W ;

Pagenstecher, C ;

McLeod, DR ;

Graham, GE ;

Mangold, E ;

Santer, R ;

Propping, P ;

Friedl, W .

HUMAN MUTATION, 2005, 26 (06) :513-519

[2] Peutz-Jeghers syndrome: a systematic review and recommendations for management [J].

Beggs, A. D. ;

Latchford, A. R. ;

Vasen, H. F. A. ;

Moslein, G. ;

Alonso, A. ;

Aretz, S. ;

Bertario, L. ;

Blanco, I. ;

Bulow, S. ;

Burn, J. ;

Capella, G. ;

Colas, C. ;

Friedl, W. ;

Moller, P. ;

Hes, F. J. ;

Jarvinen, H. ;

Mecklin, J-P ;

Nagengast, F. M. ;

Parc, Y. ;

Phillips, R. K. S. ;

Hyer, W. ;

de Leon, M. Ponz ;

Renkonen-Sinisalo, L. ;

Sampson, J. R. ;

Stormorken, A. ;

Tejpar, S. ;

Thomas, H. J. W. ;

Wijnen, J. T. ;

Clark, S. K. ;

Hodgson, S. V. .

GUT, 2010, 59 (07) :975-986

[3] Very high risk of cancer in familial Peutz-Jeghers syndrome [J].

Giardiello, FM ;

Brensinger, JD ;

Tersmette, AC ;

Goodman, SN ;

Petersen, GM ;

Booker, SV ;

Cruz-Correa, M ;

Offerhaus, JA .

GASTROENTEROLOGY, 2000, 119 (06) :1447-1453

[4]

Momin Yasmin Altaf, 2013, Int J Appl Basic Med Res, V3, P126, DOI 10.4103/2229-516X.117093

[5] Management of Ovarian and Testicular Sex Cord-stromal Tumors in Children and Adolescents [J].

Schultz, Kris Ann P. ;

Schneider, Dominik T. ;

Pashankar, Farzana ;

Ross, Jonathan ;

Frazier, Lindsay .

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 2012, 34 :S55-S63

[6] OVARIAN SEX CORD TUMOR WITH ANNULAR TUBULES - A REPORT OF 6 CASES [J].

SHEN, K ;

WU, PC ;

LANG, JH ;

HUANG, RL ;

TANG, MT ;

LIAN, LJ .

GYNECOLOGIC ONCOLOGY, 1993, 48 (02) :180-184

[7]

Tandon Rimpy, 2007, MedGenMed, V9, P44

[8] High Cancer Risk in Peutz-Jeghers Syndrome: A Systematic Review and Surveillance Recommendations [J].

van Lier, M. G. F. ;

Wagner, A. ;

Mathus-Vliegen, E. M. H. ;

Kuipers, E. J. ;

Steyerberg, E. W. ;

van Leerdam, M. E. .

AMERICAN JOURNAL OF GASTROENTEROLOGY, 2010, 105 (06) :1258-1264

[9]

YOUNG RH, 1982, CANCER, V50, P1384, DOI 10.1002/1097-0142(19821001)50:7<1384::AID-CNCR2820500726>3.0.CO

[10]

2-5

← 1 →