BLOOD LEVEL PROFILE IN MAN FOLLOWING CHRONIC ORAL-ADMINISTRATION OF FLURAZEPAM HYDROCHLORIDE

被引：122

作者：

KAPLAN, SA ^{[1
]}

SILVA, JAF ^{[1
]}

JACK, MI ^{[1
]}

ALEXANDER, K ^{[1
]}

STROJNY, N ^{[1
]}

WEINFELD, RE ^{[1
]}

PUGLISI, CV ^{[1
]}

WEISSMAN, L ^{[1
]}

机构：

[1] HOFFMAN LA ROCHE INC, DEPT BIOCHEM & DRUG METABOLISM, NUTLEY, NJ 07110 USA

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 1973年 / 62卷 / 12期

关键词：

D O I：

10.1002/jps.2600621205

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1932 / 1935

页数：4

共 6 条

[1]

BIELMANN P, 1972, INT J CLIN PHARM TH, V6, P13

[2] QUINAZOLINES AND 1,4-BENZODIAZEPINES .40. SYNTHESIS OF METABOLITES OF 7-CHLORO-1-(2-DIETHYLAMINOETHYL)-5-(2-FLUOROPHENYL)-1,3-DIHYDRO-2H-1,4-BENZODIAZEPIN-2-ONE [J].

EARLEY, JV ;

FRYER, RI ;

WINTER, D ;

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[3] METABOLISM OF FLURAZEPAM, A BENZODIAZEPINE, IN MAN AND DOG [J].

SCHWARTZ, MA ;

POSTMA, E .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1970, 59 (12) :1800-&

[4] URINARY METABOLITES OF 7-CHLORO-1-(2-DIETHYLAMINOETHYL)-5-(2-FLUOROPHENYL)-1,3-DIHYDRO-2H-1,4-BENZODIAZEPIN-2-ONE DIHYDROCHLORIDE [J].

SCHWARTZ, MA ;

VANE, FM ;

POSTMA, E .

JOURNAL OF MEDICINAL CHEMISTRY, 1968, 11 (04) :770-&

[5]

SILVA JAF, 1971, J PHARM SCI, V60, P1303

[6] QUINAZOLINES AND 1,4-BENZODIAZEPINES .25. STRUCTURE-ACTIVITY RELATIONSHIPS OF AMINOALKLY-SUBSTITUTED 1,4-BENZODIAZEPIN-2-ONES [J].

STERNBAC.LH ;

ARCHER, GA ;

EARLEY, JV ;

FRYER, RI ;

REEDER, E ;

WASYLIW, N ;

RANDALL, LO ;

BANZIGER, R .

JOURNAL OF MEDICINAL CHEMISTRY, 1965, 8 (06) :815-&

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