A NEW CLASS OF NONPEPTIDIC CHOLECYSTOKININ-B GASTRIN RECEPTOR ANTAGONISTS BASED ON DIBENZOBICYCLO[2.2.2]OCTANE

被引：19
作者：
KALINDJIAN, SB
BODKIN, MJ
BUCK, IM
DUNSTONE, DJ
LOW, CMR
MCDONALD, IM
PETHER, MJ
STEEL, KIM
机构：
来源：
JOURNAL OF MEDICINAL CHEMISTRY | 1994年 / 37卷 / 22期
关键词：
D O I：
10.1021/jm00048a001
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
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页码：3671 / 3673
页数：3
相关论文
共 18 条
[1]   BENZODIAZEPINE GASTRIN AND BRAIN CHOLECYSTOKININ RECEPTOR LIGANDS - L-365,260 [J].
BOCK, MG ;
DIPARDO, RM ;
EVANS, BE ;
RITTLE, KE ;
WHITTER, WL ;
VEBER, DF ;
ANDERSON, PS ;
FREIDINGER, RM .
JOURNAL OF MEDICINAL CHEMISTRY, 1989, 32 (01) :13-16
[2]  
Diels O, 1931, LIEBIGS ANN CHEM, V486, P191
[3]   DESIGN OF POTENT, ORALLY EFFECTIVE, NONPEPTIDAL ANTAGONISTS OF THE PEPTIDE-HORMONE CHOLECYSTOKININ [J].
EVANS, BE ;
BOCK, MG ;
RITTLE, KE ;
DIPARDO, RM ;
WHITTER, WL ;
VEBER, DF ;
ANDERSON, PS ;
FREIDINGER, RM .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (13) :4918-4922
[4]  
FOURNIEZALUSKI MC, 1985, BIOPOLYMERS, P1663
[5]   PEPTIDOMIMETICS FOR RECEPTOR LIGANDS DISCOVERY, DEVELOPMENT, AND MEDICAL PERSPECTIVES [J].
GIANNIS, A .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 1993, 32 (09) :1244-1267
[6]   CONSTITUTION + PROPERTIES OF 2 GASTRINS EXTRACTED FROM HOG ANTRAL MUCOSA .I. ISOLATION OF 2 GASTRINS FROM HOG ANTRAL MUCOSA .2. PROPERTIES OF 2 GASTRINS ISOLATED FROM HOG ANTRAL MUCOSA [J].
GREGORY, RA ;
TRACY, HJ .
GUT, 1964, 5 (02) :103-&
[7]  
HIRSCHMANN R, 1993, J AM CHEM SOC, V115, P12250
[8]   RATIONALLY DESIGNED DIPEPTOID ANALOGS OF CCK - ALPHA-METHYLTRYPTOPHAN DERIVATIVES AS HIGHLY SELECTIVE AND ORALLY ACTIVE GASTRIN AND CCK-B ANTAGONISTS WITH POTENT ANXIOLYTIC PROPERTIES [J].
HORWELL, DC ;
HUGHES, J ;
HUNTER, JC ;
PRITCHARD, MC ;
RICHARDSON, RS ;
ROBERTS, E ;
WOODRUFF, GN .
JOURNAL OF MEDICINAL CHEMISTRY, 1991, 34 (01) :404-414
[9]   DIPHENYLPYRAZOLIDINONE AND BENZODIAZEPINE CHOLECYSTOKININ ANTAGONISTS - A CASE OF CONVERGENT EVOLUTION IN MEDICINAL CHEMISTRY [J].
HOWBERT, JJ ;
LOBB, KL ;
BRITTON, TC ;
MASON, NR ;
BRUNS, RF .
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1993, 3 (05) :875-880
[10]   DEVELOPMENT OF A CLASS OF SELECTIVE CHOLECYSTOKININ TYPE-B RECEPTOR ANTAGONISTS HAVING POTENT ANXIOLYTIC ACTIVITY [J].
HUGHES, J ;
BODEN, P ;
COSTALL, B ;
DOMENEY, A ;
KELLY, E ;
HORWELL, DC ;
HUNTER, JC ;
PINNOCK, RD ;
WOODRUFF, GN .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (17) :6728-6732
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