Magnesium sulphate as an adjuvant to bupivacaine in ultrasound-guided transversus abdominis plane block in patients scheduled for total abdominal hysterectomy under subarachnoid block

被引:17
作者
Rana, Shelly [1 ]
Verma, Ravinder Kumar [1 ]
Singh, Jai [1 ]
Chaudhary, Sudarshan Kumar [1 ]
Chandel, Ankita [1 ]
机构
[1] DRPGMC, Dept Anaesthesia, Kangra, Himachal Prades, India
关键词
Adjuvants; anaesthesia; analgesia; magnesium sulphate; pain; postoperative;
D O I
10.4103/0019-5049.177879
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Background and Aims: Transversus abdominis plane (TAP) block has proven to be an effective component of multimodal analgesic regimens for a variety of abdominal procedures. Magnesium sulphate (MgSO4) N-methyl-D-aspartate receptor antagonist has the potential to be an ideal adjuvant in TAP block. We studied the efficacy of MgSO4as an adjuvant to bupivacaine in TAP block in patients scheduled for total abdominal hysterectomy (TAH) under subarachnoid block (SAB). Methods: Sixty-five women belonging to American Society of Anesthesiologists physical status 1 or 2, aged between 35 and 70 years, scheduled for TAH under SAB were recruited. Patients in Group B (n = 32) received 18 mL 0.25% bupivacaine (45 mg) with 2 mL normal saline (NS), whereas those in Group BM (n = 33) received 18 mL 0.25% bupivacaine (45 mg) with 1.5 mL (150 mg) MgSO4and 0.5 mL NS in the ultrasound (USG)-guided TAP block performed on each side after the completion of the surgery under SAB. They were evaluated for pain at 0, 2, 4, 6, 12 and 24 h, time to first rescue analgesic and duration of postoperative analgesia were noted. Results: The post-operative visual analogue scale (VAS) scores were lower in Group BM at 4, 6 and 12 h (P 0.05). Mean duration of analgesia was significantly prolonged in Group BM with lesser requirement of rescue analgesic (P 0.05) up to 12 h. Conclusion: MgSO4 (150 mg) as an adjuvant to bupivacaine in USG-guided TAP block reduces post-operative pain scores, prolongs the duration of analgesia and decreases demands for rescue analgesics.
引用
收藏
页码:174 / 179
页数:6
相关论文
共 13 条
[1]   Addition of dexmedetomidine to bupivacaine in transversus abdominis plane block potentiates post-operative pain relief among abdominal hysterectomy patients: A prospective randomized controlled trial [J].
Almarakbi, Waleed A. ;
Kaki, Abdullah M. .
SAUDI JOURNAL OF ANAESTHESIA, 2014, 8 (02) :161-166
[2]   Effect of adding dexamethasone to bupivacaine on transversus abdominis plane block for abdominal hysterectomy: A prospective randomized controlled trial [J].
Ammar, Amany S. ;
Mahmoud, Khaled M. .
SAUDI JOURNAL OF ANAESTHESIA, 2012, 6 (03) :229-233
[3]   The efficacy of ultrasound-guided transversus abdominis plane block in patients undergoing hysterectomy [J].
Atim, A. ;
Bilgin, F. ;
Kilickaya, O. ;
Purtuloglu, T. ;
Alanbay, I. ;
Orhan, M. E. ;
Kurt, E. .
ANAESTHESIA AND INTENSIVE CARE, 2011, 39 (04) :630-634
[4]   Intra-articular magnesium is effective for postoperative analgesia in arthroscopic knee surgery [J].
Bondok, R. S. ;
Abd El-Hady, A. M. .
BRITISH JOURNAL OF ANAESTHESIA, 2006, 97 (03) :389-392
[5]   Chronic pain after hysterectomy [J].
Brandsborg, B. ;
Nikolajsen, L. ;
Kehlet, H. ;
Jensen, T. S. .
ACTA ANAESTHESIOLOGICA SCANDINAVICA, 2008, 52 (03) :327-331
[6]   Activation of peripheral NMDA receptors contributes to human pain and rat afferent discharges evoked by injection of glutamate into the masseter muscle [J].
Cairns, BE ;
Svensson, P ;
Wang, KL ;
Hupfeld, S ;
Graven-Nielsen, T ;
Sessle, BJ ;
Berde, CB ;
Arendt-Nielsen, L .
JOURNAL OF NEUROPHYSIOLOGY, 2003, 90 (04) :2098-2105
[7]   Magnesium sulfate in femoral nerve block, does postoperative analgesia differ? A comparative study [J].
Elshamaa, Hossam A. ;
Ibrahim, Mohamed ;
Eldesuky, Hossam L. .
EGYPTIAN JOURNAL OF ANAESTHESIA, 2014, 30 (02) :169-173
[8]   Evaluation of the effect of magnesium sulphate vs. clonidine as adjunct to epidural bupivacaine [J].
Ghatak, Tanmoy ;
Chandra, Girish ;
Malik, Anita ;
Singh, Dinesh ;
Bhatia, Vinod Kumar .
INDIAN JOURNAL OF ANAESTHESIA, 2010, 54 (04) :308-313
[9]  
Goyal P, 2008, INTERNET J ANESTHESI
[10]   Magnesium added to prilocaine prolongs the duration of axillary plexus block [J].
Gunduz, Aytac ;
Bilir, Ayten ;
Gulec, Sacit .
REGIONAL ANESTHESIA AND PAIN MEDICINE, 2006, 31 (03) :233-236