2-ACETYLPYRROLE, A HEPATOPROTECTIVE COMPOUND FROM STREPTOMYCES SP A-5071

被引：5

作者：

ITO, M

SHIMURA, H

WATANABE, N

TAMAI, M

TAKAHASHI, A

TANAKA, Y

ARAI, I

HANADA, K

机构：

[1] Research Center, Taisho Pharmaceutical Co., Ltd., Ohmiya, Saitama, 330

[2] Department of Applied Biological Chemistry, Shizuoka University, Shizuoka, Shizuoka, 422

来源：

AGRICULTURAL AND BIOLOGICAL CHEMISTRY | 1991年 / 55卷 / 08期

关键词：

D O I：

10.1080/00021369.1991.10870903

中图分类号：

S3 [农学（农艺学）];

学科分类号：

0901 ;

摘要：

2-Acetylpyrrole, which was isolated from a culture broth of Streptomyces sp. A-5071, was found to protect primary cultured rat hepatocytes against D-galactosamine (GalN) cytotoxicity. This compound was also effective against GalN-induced liver injury in rats and against carbon tetrachloride (CCl4)-induced liver injury in mice.

引用

页码：2117 / 2121

页数：5

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