MODIFIED HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC METHOD FOR ANALYSIS OF DROTAVERINE IN HUMAN PLASMA

被引：33
作者：
LALLA, JK
SHAH, MU
JAIN, MB
SHARMA, AH
机构：
[1] Principal K.M. Kundnani College of Pharmacy, Plot No. 47, Dr R.G. Thadani Marg, Worli Sea Face
来源：
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | 1993年 / 11卷 / 4-5期
关键词：
DROTAVERINE; PAPAVERINE; PLASMA SAMPLES; HPLC ASSAY;
D O I：
10.1016/0731-7085(93)80033-W
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
An HPLC method is described for the determination of drotaverine in plasma; papaverine is used as the internal standard. The lower limit of quantitation is 50 ng ml-1 with an inter-assay precision (RSD) of below 4%. The method has been validated and successfully used to assay clinical trial samples in healthy volunteers.
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页码：385 / 388
页数：4
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