ERROR IN SMOKING MEASURES - EFFECTS OF INTERVENTION ON RELATIONS OF COTININE AND CARBON-MONOXIDE TO SELF-REPORTED SMOKING

被引:159
作者
MURRAY, RP
CONNETT, JE
LAUGER, GG
VOELKER, HT
机构
[1] UNIV MINNESOTA,SCH PUBL HLTH,MINNEAPOLIS,MN 55455
[2] AMER CYANAMID CO,LEDERLE LABS,PEARL RIVER,NY 10965
关键词
D O I
10.2105/AJPH.83.9.1251
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Objectives. Sources of measurement error in assessing smoking status are examined. Methods. The Lung Health Study, a randomized trial in 10 clinical centers, includes 3923 participants in a smoking cessation program and 1964 usual care participants. Smoking at first annual follow-up was assessed by salivary cotinine, expired air carbon monoxide, and self-report. Each of these measures is known to contain some error. Sensitivity and specificity were calculated by comparing a biochemical measure with self-report to produce an undifferentiated estimate of error. Classification error rates due to imprecision of the biochemical measures and to the error in self-report were estimated separately. Results. For cotinine compared with self-report, the sensitivity was 99.0% and the specificity 91.5%. For carbon monoxide compared with self-report, the sensitivity was 93.7% and the specificity 87.2%. The classification error attributed to self-report, estimated by comparing the results from intervention and control groups, was associated with the responses of 3% and 5% of participants, indicating a small but significant bias toward a socially desirable response. Conclusions. In absolute terms in these data, both types of error were small.
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页码:1251 / 1257
页数:7
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