CONTROLLED RELEASE STUDY OF CEFTRIAXONE FROM MCM-41-NH2 MESOPOROUS MATERIAL

被引:0
作者
Mihaiescu, Dan Eduard [1 ]
Gudovan, Dragos [1 ]
Andronescu, Ecaterina [1 ]
机构
[1] Univ Politehn Bucuresti, Fac Appl Chem & Mat Sci, Bucharest, Romania
来源
UNIVERSITY POLITEHNICA OF BUCHAREST SCIENTIFIC BULLETIN SERIES B-CHEMISTRY AND MATERIALS SCIENCE | 2015年 / 77卷 / 02期
关键词
Ceftriaxone; MCM-41-NH2; mesoporous; controlled release;
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The present article focuses on the synthesis of the Ceftriaxone loaded MCM41-NH2 based materials and the determination of the release profile of Ceftriaxone from these materials. The optimum amount was assessed through progressive loading of the MCM-41 material. A calibration curve was used for the determination of the released quantity. We also assessed the best temperature for the functionalization reaction. The obtained release profile is almost linear for lower concentrations of cetriaxone deposited in the porous channels.
引用
收藏
页码:19 / 28
页数:10
相关论文
共 23 条
  • [1] Al-Sawaad HZ, 2013, INT J ELECTROCHEM SC, V8, P3105
  • [2] The Drug Release Study of Ceftriaxone from Porous Hydroxyapatite Scaffolds
    Al-Sokanee, Zeki N.
    Toabi, Abedl Amer H.
    Al-Assadi, Mohammed J.
    Alassadi, Erfan A. S.
    [J]. AAPS PHARMSCITECH, 2009, 10 (03): : 772 - 779
  • [3] Alonge TO, 2000, INT J CLIN PRACT, V54, P353
  • [4] The Sol-Gel Route to Advanced Silica-Based Materials and Recent Applications
    Ciriminna, Rosaria
    Fidalgo, Alexandra
    Pandarus, Valerica
    Beland, Francois
    Ilharco, Laura M.
    Pagliaro, Mario
    [J]. CHEMICAL REVIEWS, 2013, 113 (08) : 6592 - 6620
  • [5] Dynamic properties in CO2 adsorption on amine-modified MCM-41
    Gao, Fei
    Zhou, Jianhai
    Bian, Zijun
    Jing, Changyong
    Hu, Jun
    Liu, Honglai
    [J]. PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART E-JOURNAL OF PROCESS MECHANICAL ENGINEERING, 2013, 227 (E2) : 106 - 116
  • [6] Comparison of Neisseria gonorrhoeae MICs obtained by Etest and agar dilution for ceftriaxone, cefpodoxime, cefixime and azithromycin
    Gose, Severin
    Kong, Carol J.
    Lee, Yer
    Samuel, Michael C.
    Bauer, Heidi M.
    Dixon, Paula
    Soge, Olusegun O.
    Lei, John
    Pandori, Mark
    [J]. JOURNAL OF MICROBIOLOGICAL METHODS, 2013, 95 (03) : 379 - 380
  • [7] Cyclodextrin-modified MCM-41 for selective double bond migration
    Jeon, Jong-Ki
    Park, Young-Kwon
    Yim, Jin-Heong
    [J]. RESEARCH ON CHEMICAL INTERMEDIATES, 2010, 36 (6-7) : 661 - 667
  • [8] Ceftriaxone Restores Glutamate Homeostasis and Prevents Relapse to Cocaine Seeking
    Knackstedt, Lori A.
    Melendez, Roberto I.
    Kalivas, Peter W.
    [J]. BIOLOGICAL PSYCHIATRY, 2010, 67 (01) : 81 - 84
  • [9] Monodispersed MCM-41 large particles by modified pseudomorphic transformation: Direct diamine functionalization and application in protein bioseparation
    Liu, Xianbin
    Du, Yu
    Guo, Zhen
    Gunasekaran, Saranya
    Ching, Chi-Bun
    Chen, Yuan
    Leong, Susanna Su Jan
    Yang, Yanhui
    [J]. MICROPOROUS AND MESOPOROUS MATERIALS, 2009, 122 (1-3) : 114 - 120
  • [10] Preparation of spherical MCM-41 molecular sieve at room temperature: Influence of the synthesis conditions in the structural properties
    Melendez-Ortiz, H. I.
    Garcia-Cerda, L. A.
    Olivares-Maldonado, Y.
    Castruita, G.
    Mercado-Silva, J. A.
    Perera-Mercado, Y. A.
    [J]. CERAMICS INTERNATIONAL, 2012, 38 (08) : 6353 - 6358