BROMOCRIPTINE-INDUCED MODULATION OF PLASMA-ALDOSTERONE RESPONSE TO ACUTE STIMULATIONS

被引：51

作者：

BIRKHAUSER, M ^{[1
]}

RIONDEL, A ^{[1
]}

VALLOTTON, MB ^{[1
]}

机构：

[1] HOP CANTONAL,DEPT MED,DIV ENDOCRINOL,INVEST CLIN LAB,CH-1211 GENEVA 4,SWITZERLAND

来源：

ACTA ENDOCRINOLOGICA | 1979年 / 91卷 / 02期

关键词：

D O I：

10.1530/acta.0.0910294

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The influence of the dopaminergic agent 2-bromoergocryptine on plasma aldosterone response to acute stimulations was assessed in 14 male volunteers. Without modifying basal plasma aldosterone levels or urinary aldosterone excretion, bromocriptine retarded and diminished significantly the plasma aldosterone response to angiotensin II or ACTH, but did not alter the response to upright posture. These results point to a bromocriptine-induced modulation of the plasma aldosterone response to direct stimulations at the adrenal level. The present work brings further evidence for an effect of the dopaminergic system on the physiological control of aldosterone.

引用

页码：294 / 302

页数：9