DETERMINATION OF N-HYDROXY AND PHENOLIC METABOLITES OF DRUGS DERIVED FROM ACETANILIDE BY O-ALKYLATION AND SELECTED ION MONITORING

被引：19
作者：
KAPETANOVIC, IM
DUTCHER, JS
STRONG, JM
机构：
[1] NORTHWESTERN UNIV,SCH MED,DEPT PHARMACOL,CHICAGO,IL 60611
[2] NORTHWESTERN UNIV,SCH MED,CTR CLIN PHARMACOL,CHICAGO,IL 60611
来源：
ANALYTICAL CHEMISTRY | 1977年 / 49卷 / 12期
关键词：
D O I：
10.1021/ac50020a051
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
引用
收藏
页码：1843 / 1846
页数：4
相关论文
共 27 条
[11]  
LEENHEER AP, 1976, ANAL CHEM, V48, P2203
[12]   ROLE OF MIXED-FUNCTION AMINE OXIDASE IN N-HYDROXYLATION OF 2-ACETAMIDOFLUORENE BY HAMSTER LIVER MICROSOMAL PREPARATIONS [J].
LOTLIKAR, PD ;
WERTMAN, K ;
LUHA, L .
BIOCHEMICAL JOURNAL, 1973, 136 (04) :1137-1140
[13]  
LOWRY OH, 1951, J BIOL CHEM, V193, P265
[14]  
LU AYH, 1969, J BIOL CHEM, V244, P3714
[15]  
MILLER JA, 1970, CANCER RES, V30, P559
[16]  
MITCHELL JR, 1975, GASTROENTEROLOGY, V68, P392
[17]  
OMURA T, 1964, J BIOL CHEM, V239, P2379
[18]  
PRESCOTT LF, 1970, CLIN PHARMACOL THER, V11, P496
[19]   PREPARATION AND PROPERTIES OF SOME N-ARYL HYDROXAMIC ACIDS [J].
PRIYADARSHINI, U ;
TANDON, SG .
JOURNAL OF CHEMICAL AND ENGINEERING DATA, 1967, 12 (01) :143-+
[20]   N-OXIDATION OF CERTAIN AROMATIC-AMINES, ACETAMIDES, AND NITRO-COMPOUNDS BY MONKEYS AND DOGS [J].
RADOMSKI, JL ;
CONZELMAN, GM ;
REY, AA ;
BRILL, E .
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1973, 50 (04) :989-995
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