ELEVATED LEVELS OF INTERLEUKIN-8 AND LEUKOTRIENE B-4 IN PULMONARY-EDEMA FLUID OF A PATIENT WITH REEXPANSION PULMONARY-EDEMA

被引：46

作者：

NAKAMURA, H ^{[1
]}

ISHIZAKA, A ^{[1
]}

SAWAFUJI, M ^{[1
]}

URANO, T ^{[1
]}

FUJISHIMA, S ^{[1
]}

SAKAMAKI, F ^{[1
]}

SAYAMA, K ^{[1
]}

KAWAMURA, M ^{[1
]}

KATO, R ^{[1
]}

KIKUCHI, K ^{[1
]}

KANAZAWA, M ^{[1
]}

KOBAYASHI, K ^{[1
]}

KAWASHIRO, T ^{[1
]}

机构：

[1] KEIO UNIV,SCH MED,DEPT SURG & MED,TOKYO,JAPAN

来源：

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE | 1994年 / 149卷 / 04期

关键词：

D O I：

10.1164/ajrccm.149.4.8143038

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

We experienced a case of reexpansion pulmonary edema (RPE) after surgical treatment of pneumothorax. In this case, protein leakage and polymorphonuclear leukocyte (PMN) accumulation were observed in the reexpanded lung. Interleukin-8 and leukotriene B-4 in edema fluid were increased at the onset of RPE. PMN elastase was also increased, though its peak was delayed. The plasma level of P-selectin, which mediates adhesion between PMN and endothelium, was elevated. We speculate that some of these fluid mediators may play important roles in chemotaxis and activation of PMN in the development of RPE.

引用

收藏

页码：1037 / 1040

页数：4

相关论文

共 16 条

[1] INCREASE IN VASCULAR-PERMEABILITY INDUCED BY LEUKOTRIENE-B4 AND THE ROLE OF POLYMORPHONUCLEAR LEUKOCYTES [J].

BJORK, J ;

HEDQVIST, P ;

ARFORS, KE .

INFLAMMATION, 1982, 6 (02) :189-200

[2] INTERLEUKIN-8 AND DEVELOPMENT OF ADULT RESPIRATORY-DISTRESS SYNDROME IN AT-RISK PATIENT GROUPS [J].

DONNELLY, SC ;

STRIETER, RM ;

KUNKEL, SL ;

WALZ, A ;

ROBERTSON, CR ;

CARTER, DC ;

GRANT, IS ;

POLLOK, AJ ;

HASLETT, C .

LANCET, 1993, 341 (8846) :643-647

[3] CHARACTERIZATION OF GMP-140 (P-SELECTIN) AS A CIRCULATING PLASMA-PROTEIN [J].

DUNLOP, LC ;

SKINNER, MP ;

BENDALL, LJ ;

FAVALORO, EJ ;

CASTALDI, PA ;

GORMAN, JJ ;

GAMBLE, JR ;

VADAS, MA ;

BERNDT, MC .

JOURNAL OF EXPERIMENTAL MEDICINE, 1992, 175 (04) :1147-1150

[4] NEUTROPHILS IN REEXPANSION PULMONARY-EDEMA [J].

JACKSON, RM ;

VEAL, CF ;

ALEXANDER, CB ;

BRANNEN, AL ;

FULMER, JD .

JOURNAL OF APPLIED PHYSIOLOGY, 1988, 65 (01) :228-234

[5] 7S-COLLAGEN IN BRONCHOALVEOLAR LAVAGE FLUID OF PATIENTS WITH ADULT RESPIRATORY-DISTRESS SYNDROME [J].

KONDOH, Y ;

TANIGUCHI, H ;

TAKI, F ;

TAKAGI, K ;

SATAKE, T .

CHEST, 1992, 101 (04) :1091-1094

[6] RE-EXPANSION PULMONARY-EDEMA [J].

MAHAJAN, VK ;

SIMON, M ;

HUBER, GL .

CHEST, 1979, 75 (02) :192-194

[7] EFFECTS OF LEUKOTRIENE-B4 IN THE HUMAN-LUNG - RECRUITMENT OF NEUTROPHILS INTO THE ALVEOLAR SPACES WITHOUT A CHANGE IN PROTEIN PERMEABILITY [J].

MARTIN, TR ;

PISTORESE, BP ;

CHI, EY ;

GOODMAN, RB ;

MATTHAY, MA .

JOURNAL OF CLINICAL INVESTIGATION, 1989, 84 (05) :1609-1619

[8] ELEVATED CONCENTRATIONS OF LEUKOTRIENE-D4 IN PULMONARY-EDEMA FLUID OF PATIENTS WITH THE ADULT RESPIRATORY-DISTRESS SYNDROME [J].

MATTHAY, MA ;

ESCHENBACHER, WL ;

GOETZL, EJ .

JOURNAL OF CLINICAL IMMUNOLOGY, 1984, 4 (06) :479-483

[9] MODULATION OF AIRWAY INFLAMMATION IN CYSTIC-FIBROSIS - INVIVO SUPPRESSION OF INTERLEUKIN-8 LEVELS ON THE RESPIRATORY EPITHELIAL SURFACE BY AEROSOLIZATION OF RECOMBINANT SECRETORY LEUKOPROTEASE INHIBITOR [J].

MCELVANEY, NG ;

NAKAMURA, H ;

BIRRER, P ;

HEBERT, CA ;

WONG, WL ;

ALPHONSO, M ;

BAKER, JB ;

CATALANO, MA ;

CRYSTAL, RG .

JOURNAL OF CLINICAL INVESTIGATION, 1992, 90 (04) :1296-1301

[10] TUMOR NECROSIS FACTOR IN BRONCHOPULMONARY SECRETIONS OF PATIENTS WITH ADULT RESPIRATORY-DISTRESS SYNDROME [J].

MILLAR, AB ;

SINGER, M ;

MEAGER, A ;

FOLEY, NM ;

JOHNSON, NM ;

ROOK, GAW .

LANCET, 1989, 2 (8665) :712-714