ENZYME-CATALYZED OLIGOSACCHARIDE SYNTHESIS

被引：277
作者：
ICHIKAWA, Y
LOOK, GC
WONG, CH
机构：
[1] Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037
来源：
ANALYTICAL BIOCHEMISTRY | 1992年 / 202卷 / 02期
关键词：
D O I：
10.1016/0003-2697(92)90099-S
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Cell-surface carbohydrates and their conjugates are involved in many types of molecular recognition. This review describes recent developments in enzyme-catalyzed oligosaccharide synthesis, with particular focus on glycosyltransferase and glycosidase reactions. With the increasing availability of glycosyltransferases via recombinant DNA technology, glycosyltransferase-catalyzed glycosylation with in situ regeneration of sugar nucleotides appears to be the most effective method for large-scale stereocontrolled oligosaccharide synthesis. © 1992.
引用
收藏
页码：215 / 238
页数：24
相关论文
共 183 条
[1]   THE SYNTHESIS OF OLIGOSACCHARIDES BY THE REVERSED HYDROLYSIS REACTION OF BETA-GLUCOSIDASE AT HIGH SUBSTRATE CONCENTRATION AND AT HIGH-TEMPERATURE [J].
AJISAKA, K ;
NISHIDA, H ;
FUJIMOTO, H .
BIOTECHNOLOGY LETTERS, 1987, 9 (04) :243-248
[2]   USE OF AN ACTIVATED CARBON COLUMN FOR THE SYNTHESIS OF DISACCHARIDES BY USE OF A REVERSED HYDROLYSIS ACTIVITY OF BETA-GALACTOSIDASE [J].
AJISAKA, K ;
NISHIDA, H ;
FUJIMOTO, H .
BIOTECHNOLOGY LETTERS, 1987, 9 (06) :387-392
[3]  
ALESSANDRINI A, 1956, J BIOL CHEM, V220, P71
[4]   TRANSFERRING ACTIVITY OF BETA-FRUCTOFURANOSIDASE FROM YEAST - A QUANTITATIVE DESCRIPTION [J].
ANDERSEN, B ;
THIESEN, N ;
BROE, PE .
ACTA CHEMICA SCANDINAVICA, 1969, 23 (07) :2367-&
[5]  
ASHWELL G, 1974, ADV ENZYMOL RAMB, V41, P99
[6]   SYNTHESIS WITH IMMOBILIZED ENZYMES OF 2 TRISACCHARIDES, ONE OF THEM ACTIVE AS THE DETERMINANT OF A STAGE ANTIGEN [J].
AUGE, C ;
DAVID, S ;
MATHIEU, C ;
GAUTHERON, C .
TETRAHEDRON LETTERS, 1984, 25 (14) :1467-1470
[7]   AN EFFICIENT SYNTHESIS OF CYTIDINE MONOPHOSPHO-SIALIC ACIDS WITH 4 IMMOBILIZED ENZYMES [J].
AUGE, C ;
GAUTHERON, C .
TETRAHEDRON LETTERS, 1988, 29 (07) :789-790
[8]   THE USE OF AN IMMOBILIZED CYCLIC MULTIENZYME SYSTEM TO SYNTHESIZE BRANCHED PENTA-SACCHARIDES AND HEXA-SACCHARIDES ASSOCIATED WITH BLOOD-GROUP I EPITOPES [J].
AUGE, C ;
MATHIEU, C ;
MERIENNE, C .
CARBOHYDRATE RESEARCH, 1986, 151 :147-156
[9]   THE USE OF IMMOBILIZED GLYCOSYLTRANSFERASES IN THE SYNTHESIS OF SIALYLOLIGOSACCHARIDES [J].
AUGE, C ;
FERNANDEZFERNANDEZ, R ;
GAUTHERON, C .
CARBOHYDRATE RESEARCH, 1990, 200 :257-268
[10]   ENZYMIC-SYNTHESIS OF THE SIALYLGLYCOPEPTIDE, ALPHA-D-NEUPAC-(2-]6)-BETA-D-GALP-(1-]4)-BETA-D-GLCPNAC-(1-]4N)-L-ASN [J].
AUGE, C ;
GAUTHERON, C ;
PORA, H .
CARBOHYDRATE RESEARCH, 1989, 193 :288-293
12345678910