IDENTIFICATION OF 2 URINARY INDOLE MELANOGENS BY THIN-LAYER CHROMATOGRAPHY

被引：8

作者：

BADINAND, A

PASQUIER, J

VALLON, JJ

GUILLUY, R

MILON, H

机构：

[1] Laboratoire Central de Chimie Biologique, Hôpital E. Herriot, Lyon, et Laboratoire de Chimie Analytique Pharmaceutique, Faculté mixte de Médecine et de Pharmacie, 8, Avenue Rockfeller

来源：

CLINICA CHIMICA ACTA | 1969年 / 25卷 / 03期

关键词：

D O I：

10.1016/0009-8981(69)90193-4

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

An indole melanogen has been identified in melanotic urine, by thin-layer bidimensional chromatography on cellulose. According to data given by Duchon and coll., this compound was presumed to be a mixture of 5-hydroxy-6-methoxy indole 2-carboxylic and 5-methoxy-6-hydroxy indole 2-carboxylic acid. This indole compound has been isolated and identified by Chromatographic, spectrophotometric and spectrofluorimetric methods, and with mass spectrometry. Thin-layer chromatography on cellulose after enzymatic hydrolysis of urines is proposed for simultaneous detection of phenol and indole melanogens. © 1969.

引用

页码：357 / &