INITIATION OF MEIOTIC RECOMBINATION IS INDEPENDENT OF INTERHOMOLOGUE INTERACTIONS

被引：44

作者：

GILBERTSON, LA ^{[1
]}

STAHL, FW ^{[1
]}

机构：

[1] UNIV OREGON,INST MOLEC BIOL,EUGENE,OR 97403

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1994年 / 91卷 / 25期

关键词：

D O I：

10.1073/pnas.91.25.11934

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

In yeast meiosis, crossing-over between homologues is dependent upon double-strand breaks. We demonstrate that the occurrence of these breaks is independent of pairing between homologues by showing that they occur with normal frequency, timing, and position in the absence of a homologue. This observation supports models that view double-strand breaks as initiating events and crossing-over as a consequence of repair of these breaks.

引用

页码：11934 / 11937

页数：4

共 27 条

[1] ANALYSIS OF WILD-TYPE AND RAD50 MUTANTS OF YEAST SUGGESTS AN INTIMATE-RELATIONSHIP BETWEEN MEIOTIC CHROMOSOME SYNAPSIS AND RECOMBINATION [J].