REPLACING SYSTEMIC WITH TOPICAL CORTICOTHERAPY IN PATIENTS WITH GENERALIZED BULLOUS PEMPHIGOID AND SERIOUS STEROID-INDUCED IATROGENESIS

被引：2
作者：
Garcia-Doval, Ignacio [1 ]
Conde, Alberto [1 ]
Mayo, Eugenia [1 ]
Cruces, Manuel J. [1 ]
机构：
[1] Complejo Hosp Pontevedra, Serv Dermatol, Pontvedra, Spain
来源：
ACTAS DERMO-SIFILIOGRAFICAS | 2006年 / 97卷 / 03期
关键词：
side effect; bullous pemphigoid; clobetasol; treatment; topical glucocorticoids;
D O I：
10.1016/S0001-7310(06)73377-4
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
We describe four patients with generalized bullous pemphigoid, who received treatment with oral prednisone and suffered serious corticosteroid-induced iatrogenesis. In all cases, we decided to quickly withdraw the systemic corticosteroid treatment and begin treatment with 0.05% clobetasol propionate (20 g/day). New outbreaks of pemphigoid or significant side effects were not seen after this change in medication. The topical treatment went on for five to twelve months, and the patients were followed up for extended periods after treatment ended, with no recurrences being observed. Systemic corticosteroid treatment may be replaced by topical treatment without complications, and this may be especially indicated in patients with serious corticosteroid-induced iatrogenesis.
引用
收藏
页码：186 / 188
页数：3
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